biostudies-literatureUnknown10Carvalho A<h4>Background and aim</h4>The kinetics of antibody production in response to coronavirus disease 2019 (COVID-19) infection is not well-defined yet. This study aimed to evaluate the antibody responses to SARS-CoV-2 and its dynamics during 9-months in a cohort of patients infected during the first phase of the pandemic. As a secondary aim, it was intended to evaluate the factors associated with different concentrations of IgG antibodies.<h4>Methods</h4>A prospective cohort study was conducted from June 2020 to January 2021. This study recruited a convenience sample of adult individuals who where recently diagnosed with COVID-19 and were living in mainland Portugal. A total of 1,695 blood samples were collected from 585 recovered COVID-19 patients up to 9 months after SARS-CoV-2 acute infectFrontiers in public health1069898https://www.ebi.ac.uk/biostudies/studies/S-EPMC9872107biostudies-literaturePersistence of IgG COVID-19 antibodies: A longitudinal analysis.PMC9872107Rodrigues AMCarvalho AGuimaraes MQueiros PMendonca Nde Sousa GHenriques ARRodrigues JCanhao HAntunes FfalsePersistence of IgG COVID-19 antibodies: A longitudinal analysis.<h4>Background and aim</h4>The kinetics of antibody production in response to coronavirus disease 2019 (COVID-19) infection is not well-defined yet. This study aimed to evaluate the antibody responses to SARS-CoV-2 and its dynamics during 9-months in a cohort of patients infected during the first phase of the pandemic. As a secondary aim, it was intended to evaluate the factors associated with different concentrations of IgG antibodies.<h4>Methods</h4>A prospective cohort study was conducted from June 2020 to January 2021. This study recruited a convenience sample of adult individuals who where recently diagnosed with COVID-19 and were living in mainland Portugal. A total of 1,695 blood samples were collected from 585 recovered COVID-19 patients up to 9 months after SARS-CoV-2 acute infect2022-01-01T00:00:00Z20222025-04-22T06:14:43.646Z2025-04-05T21:40:08.018ZS-EPMC98721073670381810.3389/fpubh.2022.1069898