biostudies-literatureUnknown13(1)Mooghali M<h4>Objective</h4>To evaluate the prevalence and accuracy of industry-related financial conflict of interest (COI) disclosures among US physician guideline authors.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Clinical practice guidelines published by the Council of Medical Specialty Societies in 2020.<h4>Participants</h4>US physician guideline authors.<h4>Main outcome measures</h4>Financial COI disclosures, both self-reported and determined using Open Payments data.<h4>Results</h4>Among 270 US physician authors of 20 clinical practice guidelines, 101 (37.4%) disclosed industry-related financial COIs, whereas 199 (73.7%) were found to have received payments from industry when accounting for payments disclosed through Open Payments. The median payments received by authors during the 3-year period was US$27 451 (IQR, US$1385-US$254 677). Comparing authors' self-disclosures with Open Payments, 72 (26.7%) of the authors accurately disclosed their financial COIs, including 68 (25.2%) accurately disclosing no financial COIs and 4 (1.5%) accurately disclosing a financial COI. In contrast, 101 (37.4%) disclosed no financial COIs and were found to have received payments from industry, 23 (8.5%) disclosed a financial COI but had under-reported payments received from industry, 14 (5.2%) disclosed a financial COI but had over-reported payments received from industry and 60 (22.2%) disclosed a financial COI but were found to have both under-reported and over-reported payments received from industry. We found that inaccurate COI disclosure was more frequent among professors compared with non-professors (81.9% vs 63.5%; p<0.001) and among males compared with females (77.7% vs 64.8%; p=0.02). The accuracy of disclosures also varied among medical professional societies (p<0.001).<h4>Conclusions</h4>Financial relationships with industry are common among US physician authors of clinical practice guidelines and are often not accurately disclosed. To ensure high-quality guidelines and unbiased recommendations, more effort is needed to minimise existing COIs and improve disclosure accuracy among panel members.BMJ opene069115https://www.ebi.ac.uk/biostudies/studies/S-EPMC9872463biostudies-literatureFinancial conflicts of interest among US physician authors of 2020 clinical practice guidelines: a cross-sectional study.PMC9872463Mooghali MGlick LRamachandran RRoss JSfalseFinancial conflicts of interest among US physician authors of 2020 clinical practice guidelines: a cross-sectional study.<h4>Objective</h4>To evaluate the prevalence and accuracy of industry-related financial conflict of interest (COI) disclosures among US physician guideline authors.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Clinical practice guidelines published by the Council of Medical Specialty Societies in 2020.<h4>Participants</h4>US physician guideline authors.<h4>Main outcome measures</h4>Financial COI disclosures, both self-reported and determined using Open Payments data.<h4>Results</h4>Among 270 US physician authors of 20 clinical practice guidelines, 101 (37.4%) disclosed industry-related financial COIs, whereas 199 (73.7%) were found to have received payments from industry when accounting for payments disclosed through Open Payments. The median payments received by authors during the 3-year period was US$27 451 (IQR, US$1385-US$254 677). Comparing authors' self-disclosures with Open Payments, 72 (26.7%) of the authors accurately disclosed their financial COIs, including 68 (25.2%) accurately disclosing no financial COIs and 4 (1.5%) accurately disclosing a financial COI. In contrast, 101 (37.4%) disclosed no financial COIs and were found to have received payments from industry, 23 (8.5%) disclosed a financial COI but had under-reported payments received from industry, 14 (5.2%) disclosed a financial COI but had over-reported payments received from industry and 60 (22.2%) disclosed a financial COI but were found to have both under-reported and over-reported payments received from industry. We found that inaccurate COI disclosure was more frequent among professors compared with non-professors (81.9% vs 63.5%; p<0.001) and among males compared with females (77.7% vs 64.8%; p=0.02). The accuracy of disclosures also varied among medical professional societies (p<0.001).<h4>Conclusions</h4>Financial relationships with industry are common among US physician authors of clinical practice guidelines and are often not accurately disclosed. To ensure high-quality guidelines and unbiased recommendations, more effort is needed to minimise existing COIs and improve disclosure accuracy among panel members.2023-01-01T00:00:00Z2023 Jan2025-04-04T12:21:00.558Z2025-04-04T12:21:00.558ZS-EPMC98724633669040210.1136/bmjopen-2022-069115