biostudies-literatureUnknown23(1)Ganesan SPatients with central vision loss (CVL) adopt an eccentric retinal location for fixation, a preferred retinal location (PRL), to compensate for vision loss at the fovea. Although most patients with CVL are able to rapidly use a PRL instead of the fovea, saccadic re-referencing to a PRL develops slowly. Without re-referencing, saccades land the saccade target in the scotoma. This results in corrective saccades and leads to inefficient visual exploration. Here, we tested a new method to train saccadic re-referencing. Healthy participants performed gaze-contingent visual search tasks with simulated central scotoma in which participants had to fixate targets with an experimenter-defined forced retinal location (FRL). In experiment 1, we compared single-target search and foraging search tasks iJournal of vision13https://www.ebi.ac.uk/biostudies/studies/S-EPMC9872842biostudies-literatureA gaze-contingent saccadic re-referencing training with simulated central vision loss.PMC9872842Melnik NAzanon EGanesan SPollmann SfalseA gaze-contingent saccadic re-referencing training with simulated central vision loss.Patients with central vision loss (CVL) adopt an eccentric retinal location for fixation, a preferred retinal location (PRL), to compensate for vision loss at the fovea. Although most patients with CVL are able to rapidly use a PRL instead of the fovea, saccadic re-referencing to a PRL develops slowly. Without re-referencing, saccades land the saccade target in the scotoma. This results in corrective saccades and leads to inefficient visual exploration. Here, we tested a new method to train saccadic re-referencing. Healthy participants performed gaze-contingent visual search tasks with simulated central scotoma in which participants had to fixate targets with an experimenter-defined forced retinal location (FRL). In experiment 1, we compared single-target search and foraging search tasks i2023-01-01T00:00:00Z2023 Jan2025-04-19T14:29:29.575Z2025-04-19T14:29:29.575ZS-EPMC98728423666250210.1167/jov.23.1.13