biostudies-literatureUnknown13Xu LQ<h4>Background</h4>Lungs were initially thought to be sterile. However, with the development of sequencing technologies, various commensal microorganisms, especially bacteria, have been observed in the lungs of healthy humans. Several studies have also linked lung microbes to infectious lung diseases. However, few databases have focused on the metagenomics of lungs to provide microbial compositions and corresponding metadata information. Such a database would be handy for researching and treating lung diseases.<h4>Methods</h4>To provide researchers with a preliminary understanding of lung microbes and their research methods, the LDMD collated nearly 10,000 studies in the literature covering over 30 diseases, gathered basic information such as the sources of lung microbe samples, sequencingFrontiers in microbiology1085079https://www.ebi.ac.uk/biostudies/studies/S-EPMC9873265biostudies-literatureLDMD: A database of microbes in human lung disease.PMC9873265Liu XQiao FYang JLi JLiang WXu LQChen JSun ZZhang QfalseLDMD: A database of microbes in human lung disease.<h4>Background</h4>Lungs were initially thought to be sterile. However, with the development of sequencing technologies, various commensal microorganisms, especially bacteria, have been observed in the lungs of healthy humans. Several studies have also linked lung microbes to infectious lung diseases. However, few databases have focused on the metagenomics of lungs to provide microbial compositions and corresponding metadata information. Such a database would be handy for researching and treating lung diseases.<h4>Methods</h4>To provide researchers with a preliminary understanding of lung microbes and their research methods, the LDMD collated nearly 10,000 studies in the literature covering over 30 diseases, gathered basic information such as the sources of lung microbe samples, sequencing2022-01-01T00:00:00Z20222025-04-21T22:07:41.199Z2025-04-05T18:36:51.402ZS-EPMC98732653670456210.3389/fmicb.2022.1085079