{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chadchan SB"],"funding":["NICHD NIH HHS","NCI NIH HHS","U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development"],"pagination":["28"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9873805"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(1)"],"pubmed_abstract":["Endometriosis is a pathological condition of the female reproductive tract characterized by the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between the age 15 and 49 in the USA. However, currently there is no reliable non-invasive method to detect the presence of endometriosis without surgery and many women find hormonal therapy and surgery as ineffective in avoiding the recurrences. There is a lack of knowledge on the etiology and the factors that contribute to the development of endometriosis. A growing body of recent evidence suggests an association between gut microbiota and endometriosis pathophysiology. However, the direct impact of microbiota and microbiota-derived metabolites on the endometriosis disease progression is largely unknown. To understan"],"journal":["Cell death discovery"],"pubmed_title":["Gut microbiota and microbiota-derived metabolites promotes endometriosis."],"pmcid":["PMC9873805"],"funding_grant_id":["R01HD065435","R00HD080742","R01 CA220297","R01 CA216426","R00 HD080742","R01 HD065435","P30 CA125123","R01 HD102680","R01HD102680"],"pubmed_authors":["Kommagani R","Putluri S","Ambati CR","Kau AL","Stallings CL","Naik SK","Popli P","Lint MA","Talwar C","Chadchan SB"],"additional_accession":[]},"is_claimable":false,"name":"Gut microbiota and microbiota-derived metabolites promotes endometriosis.","description":"Endometriosis is a pathological condition of the female reproductive tract characterized by the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between the age 15 and 49 in the USA. However, currently there is no reliable non-invasive method to detect the presence of endometriosis without surgery and many women find hormonal therapy and surgery as ineffective in avoiding the recurrences. There is a lack of knowledge on the etiology and the factors that contribute to the development of endometriosis. A growing body of recent evidence suggests an association between gut microbiota and endometriosis pathophysiology. However, the direct impact of microbiota and microbiota-derived metabolites on the endometriosis disease progression is largely unknown. To understan","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-04T13:07:40.194Z","creation":"2025-04-04T13:07:40.194Z"},"accession":"S-EPMC9873805","cross_references":{"pubmed":["36693853"],"doi":["10.1038/s41420-023-01309-0"]}}