{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Li T"],"pubmed_abstract":["<h4>Introduction</h4>Dysregulation of cell cycle progression (CCP) is a trait that distinguishes cancer from other diseases. In several cancer types, CCP-related genes serve as the primary risk factor for prognosis, but their role in cutaneous melanoma remains unclear.<h4>Methods</h4>Data from cutaneous melanoma patients were acquired from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). Using a Wilcoxon test, the level of CCP-related gene expression in cutaneous melanoma patient tissues was compared to that in normal skin tissues. Logistic analysis was then utilized to calculate the connection between the CCP-related genes and clinicopathological variables. The important functions of the CCP-related genes were further investigated using Gene Ontology (GO), Kyoto Encyclope"],"journal":["Frontiers in oncology"],"pagination":["1055308"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9876620"],"repository":["biostudies-literature"],"pubmed_title":["CDCA3 is a prognostic biomarker for cutaneous melanoma and is connected with immune infiltration."],"pmcid":["PMC9876620"],"pubmed_authors":["Yu N","Zeng A","Long X","Li T","Huang J","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"CDCA3 is a prognostic biomarker for cutaneous melanoma and is connected with immune infiltration.","description":"<h4>Introduction</h4>Dysregulation of cell cycle progression (CCP) is a trait that distinguishes cancer from other diseases. In several cancer types, CCP-related genes serve as the primary risk factor for prognosis, but their role in cutaneous melanoma remains unclear.<h4>Methods</h4>Data from cutaneous melanoma patients were acquired from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). Using a Wilcoxon test, the level of CCP-related gene expression in cutaneous melanoma patient tissues was compared to that in normal skin tissues. Logistic analysis was then utilized to calculate the connection between the CCP-related genes and clinicopathological variables. The important functions of the CCP-related genes were further investigated using Gene Ontology (GO), Kyoto Encyclope","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-07-14T19:05:40.035Z","creation":"2025-04-07T03:15:50.984Z"},"accession":"S-EPMC9876620","cross_references":{"pubmed":["36713580"],"doi":["10.3389/fonc.2022.1055308"]}}