biostudies-literatureUnknown12Li T<h4>Introduction</h4>Dysregulation of cell cycle progression (CCP) is a trait that distinguishes cancer from other diseases. In several cancer types, CCP-related genes serve as the primary risk factor for prognosis, but their role in cutaneous melanoma remains unclear.<h4>Methods</h4>Data from cutaneous melanoma patients were acquired from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). Using a Wilcoxon test, the level of CCP-related gene expression in cutaneous melanoma patient tissues was compared to that in normal skin tissues. Logistic analysis was then utilized to calculate the connection between the CCP-related genes and clinicopathological variables. The important functions of the CCP-related genes were further investigated using Gene Ontology (GO), Kyoto EncyclopeFrontiers in oncology1055308https://www.ebi.ac.uk/biostudies/studies/S-EPMC9876620biostudies-literatureCDCA3 is a prognostic biomarker for cutaneous melanoma and is connected with immune infiltration.PMC9876620Yu NZeng ALong XLi THuang JWang LfalseCDCA3 is a prognostic biomarker for cutaneous melanoma and is connected with immune infiltration.<h4>Introduction</h4>Dysregulation of cell cycle progression (CCP) is a trait that distinguishes cancer from other diseases. In several cancer types, CCP-related genes serve as the primary risk factor for prognosis, but their role in cutaneous melanoma remains unclear.<h4>Methods</h4>Data from cutaneous melanoma patients were acquired from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). Using a Wilcoxon test, the level of CCP-related gene expression in cutaneous melanoma patient tissues was compared to that in normal skin tissues. Logistic analysis was then utilized to calculate the connection between the CCP-related genes and clinicopathological variables. The important functions of the CCP-related genes were further investigated using Gene Ontology (GO), Kyoto Encyclope2022-01-01T00:00:00Z20222026-07-14T19:05:40.035Z2025-04-07T03:15:50.984ZS-EPMC98766203671358010.3389/fonc.2022.1055308