{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Johansson M"],"funding":["Universität Bielefeld","Deutsche Forschungsgemeinschaft"],"pagination":["1404"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9876914"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Arabidopsis SENSITIVITY TO RED LIGHT REDUCED 1 (SRR1) delays the transition from vegetative to reproductive development in noninductive conditions. A second-site suppressor screen for novel genes that overcome early flowering of srr1-1 identified a range of suppressor of srr1-1 mutants flowering later than srr1-1 in short photoperiods. Here, we focus on mutants flowering with leaf numbers intermediate between srr1-1 and Col. Ssm67 overcomes srr1-1 early flowering independently of day-length and ambient temperature. Full-genome sequencing and linkage mapping identified a causative SNP in a gene encoding a Haloacid dehalogenase superfamily protein, named HAD-FAMILY REGULATOR OF DEVELOPMENT AND FLOWERING 1 (HDF1). Both, ssm67 and hdf1-1 show increased levels of FLC, indicating that HDF1 is a "],"journal":["Scientific reports"],"pubmed_title":["HDF1, a novel flowering time regulator identified in a mutant suppressing sensitivity to red light reduced 1 early flowering."],"pmcid":["PMC9876914"],"funding_grant_id":["STA653/5-2","JO1252/2-1"],"pubmed_authors":["Staiger D","Steffen A","Lewinski M","Johansson M","Kobi N"],"additional_accession":[]},"is_claimable":false,"name":"HDF1, a novel flowering time regulator identified in a mutant suppressing sensitivity to red light reduced 1 early flowering.","description":"Arabidopsis SENSITIVITY TO RED LIGHT REDUCED 1 (SRR1) delays the transition from vegetative to reproductive development in noninductive conditions. A second-site suppressor screen for novel genes that overcome early flowering of srr1-1 identified a range of suppressor of srr1-1 mutants flowering later than srr1-1 in short photoperiods. Here, we focus on mutants flowering with leaf numbers intermediate between srr1-1 and Col. Ssm67 overcomes srr1-1 early flowering independently of day-length and ambient temperature. Full-genome sequencing and linkage mapping identified a causative SNP in a gene encoding a Haloacid dehalogenase superfamily protein, named HAD-FAMILY REGULATOR OF DEVELOPMENT AND FLOWERING 1 (HDF1). Both, ssm67 and hdf1-1 show increased levels of FLC, indicating that HDF1 is a ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-26T17:27:56.956Z","creation":"2025-04-06T15:29:46.036Z"},"accession":"S-EPMC9876914","cross_references":{"pubmed":["36697433"],"doi":["10.1038/s41598-023-28049-6"]}}