biostudies-literatureKalam FNIDDK NIH HHSNCI NIH HHSNational Institutes of Health57-62https://www.ebi.ac.uk/biostudies/studies/S-EPMC9877115biostudies-literatureUnknown31 Suppl 1<h4>Objective</h4>Concerns have been raised regarding the impact of time-restricted eating (TRE) on sex hormones in females. This study examined how TRE affects sex steroids in premenopausal and postmenopausal females.<h4>Methods</h4>This is a secondary analysis of an 8-week TRE study (4- to 6-hour eating window) conducted in adults with obesity. Men and perimenopausal females were excluded. Females were classified into two groups based on menstrual status: premenopausal (n = 12) or postmenopausal (n = 11).<h4>Results</h4>After 8 weeks, body weight decreased in premenopausal females (-3% ± 2%) and postmenopausal females (-4% ± 2%) (main effect of time, p < 0.001), with no difference between groups (no group × time interaction). Circulating levels of testosterone, androstenedione, and sex hObesity (Silver Spring, Md.)Effect of time-restricted eating on sex hormone levels in premenopausal and postmenopausal females.PMC9877115T32 CA193193R01 CA257807R01DK119783R01 DK119783Spring BKhan SAKalam FCienfuegos SVarady KALin SReddy SPTamatam CMAkasheh RTAnkireddy AGabel KEzpeleta MfalseEffect of time-restricted eating on sex hormone levels in premenopausal and postmenopausal females.<h4>Objective</h4>Concerns have been raised regarding the impact of time-restricted eating (TRE) on sex hormones in females. This study examined how TRE affects sex steroids in premenopausal and postmenopausal females.<h4>Methods</h4>This is a secondary analysis of an 8-week TRE study (4- to 6-hour eating window) conducted in adults with obesity. Men and perimenopausal females were excluded. Females were classified into two groups based on menstrual status: premenopausal (n = 12) or postmenopausal (n = 11).<h4>Results</h4>After 8 weeks, body weight decreased in premenopausal females (-3% ± 2%) and postmenopausal females (-4% ± 2%) (main effect of time, p < 0.001), with no difference between groups (no group × time interaction). Circulating levels of testosterone, androstenedione, and sex h2023-01-01T00:00:00Z2023 Feb2025-04-26T11:48:54.452Z2025-02-19T04:59:46.605ZS-EPMC98771153620327310.1002/oby.23562