biostudies-literatureUnknown25Li WElektaElekta ABCanadian Institutes of Health ResearchAs frameless stereotactic radiosurgery increase in use, the aim of this study was to evaluate intra-fraction motion through cone-beam CT (CBCT) and high-definition motion management (HDMM) systems. Intra-fraction motion measured between localization, repeat localization and post-treatment CBCTs were correlated to intra-faction motion indicated by the HDMM files using the Pearson coefficient (r). A total of 302 plans were reviewed from 263 patients (114 male, 149 female); 216 pairs of localization-repeat localization, and 260 localization-post-treatment CBCTs were analyzed against HDMM logs. We found the magnitude of intra-fraction motion detected by the HDMM system were larger than the corresponding CBCT results.Physics and imaging in radiation oncology100415https://www.ebi.ac.uk/biostudies/studies/S-EPMC9883231biostudies-literatureAssessment of intra-fraction motion during frameless image guided Gamma Knife stereotactic radiosurgery.PMC9883231Li WChung CLaperriere NBootsma GJaffray DACoolens CMillar BACho YBShultz DfalseAssessment of intra-fraction motion during frameless image guided Gamma Knife stereotactic radiosurgery.As frameless stereotactic radiosurgery increase in use, the aim of this study was to evaluate intra-fraction motion through cone-beam CT (CBCT) and high-definition motion management (HDMM) systems. Intra-fraction motion measured between localization, repeat localization and post-treatment CBCTs were correlated to intra-faction motion indicated by the HDMM files using the Pearson coefficient (r). A total of 302 plans were reviewed from 263 patients (114 male, 149 female); 216 pairs of localization-repeat localization, and 260 localization-post-treatment CBCTs were analyzed against HDMM logs. We found the magnitude of intra-fraction motion detected by the HDMM system were larger than the corresponding CBCT results.2023-01-01T00:00:00Z2023 Jan2026-07-09T12:17:28.161Z2025-04-05T18:49:08.305ZS-EPMC98832313671835610.1016/j.phro.2023.100415