{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["46(2)"],"submitter":["Jonas RA"],"funding":["Heart and Vascular Institute"],"pubmed_abstract":["<h4>Objective</h4>This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Whether APCs differ based on lesion severity and diabetes status is unknown.<h4>Research design and methods</h4>We retrospectively evaluated 303 subjects from the Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia (CREDENCE) trial referred for invasive coronary angiography with coronary computed tomographic angiography (CCTA) and classified lesions as obstructive (≥50% stenosed) or nonobstructive using blinded core laboratory analysis of quantitative coronary angiography. CCTA quantified APCs, including plaque volume (PV), calcified plaque (CP), noncalcified plaque (NCP), l"],"journal":["Diabetes care"],"pagination":["416-424"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9887618"],"repository":["biostudies-literature"],"pubmed_title":["Diabetes, Atherosclerosis, and Stenosis by AI."],"pmcid":["PMC9887618"],"pubmed_authors":["Jang JJ","Choi AD","Andreini D","Katz RJ","Ridner M","Shin SH","Cole J","Thompson RC","Villines TC","Koo BK","Earls JP","Avelar E","Nakazato R","Crabtree TR","Marques H","van Rosendael AR","Choi JH","Nabi F","Park HB","Stuijfzand WJ","Her AY","Al-Mallah MH","Driessen RS","Rowan C","de Waard GA","Bax JJ","Gimelli A","Knaapen P","Lu B","Min JK","Bom MJ","Jennings RS","Doh JH","Schoepf UJ","Chang HJ","Nam CW","Gao Y","Genereux P","Pontone G","Khan MA","Guglielmo M","Jonas RA"],"additional_accession":[]},"is_claimable":false,"name":"Diabetes, Atherosclerosis, and Stenosis by AI.","description":"<h4>Objective</h4>This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Whether APCs differ based on lesion severity and diabetes status is unknown.<h4>Research design and methods</h4>We retrospectively evaluated 303 subjects from the Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia (CREDENCE) trial referred for invasive coronary angiography with coronary computed tomographic angiography (CCTA) and classified lesions as obstructive (≥50% stenosed) or nonobstructive using blinded core laboratory analysis of quantitative coronary angiography. CCTA quantified APCs, including plaque volume (PV), calcified plaque (CP), noncalcified plaque (NCP), l","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-05-31T22:17:02.084Z","creation":"2024-11-09T21:36:32.119Z"},"accession":"S-EPMC9887618","cross_references":{"pubmed":["36577120"],"doi":["10.2337/dc21-1663"]}}