biostudies-literatureOpenSAFELY CollaborativeMedical Research CouncilNational Institute for Health Research (NIHR)Wellcome Truste066164https://www.ebi.ac.uk/biostudies/studies/S-EPMC9890277biostudies-literatureUnknown13(1)<h4>Objective</h4>To characterise factors associated with COVID-19 vaccine uptake among people with kidney disease in England.<h4>Design</h4>Retrospective cohort study using the OpenSAFELY-TPP platform, performed with the approval of NHS England.<h4>Setting</h4>Individual-level routine clinical data from 24 million people across GPs in England using TPP software. Primary care data were linked directly with COVID-19 vaccine records up to 31 August 2022 and with renal replacement therapy (RRT) status via the UK Renal Registry (UKRR).<h4>Participants</h4>A cohort of adults with stage 3-5 chronic kidney disease (CKD) or receiving RRT at the start of the COVID-19 vaccine roll-out was identified based on evidence of reduced estimated glomerular filtration rate (eGFR) or inclusion in the UKRR.<h4BMJ openFactors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study.PMC989027720059MR/W016729/1MC_PC_20059222097/Z/20/ZMC_PC-20059COV-LT2-0073HDR-9002MR/V015757/1MC_PC_20059-5MC_PC_20030NIHR135559MR/V015737/1MR/W021420/1Sterne JAHarper SCarr EJParry JWilliamson EJSteenkamp RTazare JHorne EMTomlinson LAGoldacre BMahalingasivam VWillicombe MZheng BHulme WJLoud FNitsch DParker EPCurtis HJNab LHester FGreen ACOpenSAFELY CollaborativeLyon SBates CMehrkar AFisher LCockburn JSanthakumaran SWalker AJfalseFactors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study.<h4>Objective</h4>To characterise factors associated with COVID-19 vaccine uptake among people with kidney disease in England.<h4>Design</h4>Retrospective cohort study using the OpenSAFELY-TPP platform, performed with the approval of NHS England.<h4>Setting</h4>Individual-level routine clinical data from 24 million people across GPs in England using TPP software. Primary care data were linked directly with COVID-19 vaccine records up to 31 August 2022 and with renal replacement therapy (RRT) status via the UK Renal Registry (UKRR).<h4>Participants</h4>A cohort of adults with stage 3-5 chronic kidney disease (CKD) or receiving RRT at the start of the COVID-19 vaccine roll-out was identified based on evidence of reduced estimated glomerular filtration rate (eGFR) or inclusion in the UKRR.<h42023-01-01T00:00:00Z2023 Jan2025-04-21T16:08:05.924Z2025-04-21T16:08:05.924ZS-EPMC98902773672056810.1136/bmjopen-2022-066164