biostudies-literatureAnto-Ocrah MNINDS NIH HHS176-187https://www.ebi.ac.uk/biostudies/studies/S-EPMC9892200biostudies-literatureUnknown141(1)<h4>Objective</h4>To evaluate how stress related to the coronavirus disease 2019 (COVID-19) pandemic has affected women's menstrual cycles. We hypothesized that women with high levels of COVID-19-related stress would have more menstrual changes compared with those with lower levels of stress.<h4>Methods</h4>Using a cross-sectional study design, we recruited a representative sample of U.S. adult women of reproductive age (18-45 years) using nonhormonal birth control to participate in an online REDCap (Research Electronic Data Capture, Vanderbilt University) survey. COVID-19-related stress was assessed with the PSS-10-C (COVID-19 Pandemic-related Perceived Stress Scale) and dichotomized as low stress (scores lower than 25) and high stress (scores 25 or higher). Self-reported menstrual outcomObstetrics and gynecologyCoronavirus Disease 2019 (COVID-19)-Related Stress and Menstrual Changes.PMC9892200T32 NS007338K01 NS121199Glantz JCAnto-Ocrah MDeSplinter LChen MTiffany KHollenbach SKaukeinen KValachovic TfalseCoronavirus Disease 2019 (COVID-19)-Related Stress and Menstrual Changes.<h4>Objective</h4>To evaluate how stress related to the coronavirus disease 2019 (COVID-19) pandemic has affected women's menstrual cycles. We hypothesized that women with high levels of COVID-19-related stress would have more menstrual changes compared with those with lower levels of stress.<h4>Methods</h4>Using a cross-sectional study design, we recruited a representative sample of U.S. adult women of reproductive age (18-45 years) using nonhormonal birth control to participate in an online REDCap (Research Electronic Data Capture, Vanderbilt University) survey. COVID-19-related stress was assessed with the PSS-10-C (COVID-19 Pandemic-related Perceived Stress Scale) and dichotomized as low stress (scores lower than 25) and high stress (scores 25 or higher). Self-reported menstrual outcom2023-01-01T00:00:00Z2023 Jan2025-04-06T19:19:04.254Z2025-04-06T19:19:04.254ZS-EPMC98922003635793010.1097/AOG.000000000000501010.1097/aog.0000000000005010