biostudies-literatureUnknown6(2)Manigault AW<h4>Importance</h4>Acoustic cry characteristics have been associated with severe medical problems in newborns. However, little is known about the utility of neonatal acoustic cry characteristics in the prediction of long-term outcomes of very preterm infants.<h4>Objectives</h4>To evaluate whether acoustic characteristics of infant cry at neonatal intensive care unit (NICU) discharge are associated with behavioral and developmental outcomes at age 2 years in infants born very preterm.<h4>Design, setting, and participants</h4>Infants born less than 30 weeks postmenstrual age (PMA) were enrolled from April 2014 through June 2016 as part of a multicenter (9 US university affiliated NICUs) cohort study and followed to adjusted age 2 years. Reported analyses began on September 2021. Data were anJAMA network opene2254151https://www.ebi.ac.uk/biostudies/studies/S-EPMC9892956biostudies-literatureAcoustic Cry Characteristics in Preterm Infants and Developmental and Behavioral Outcomes at 2 Years of Age.PMC9892956Marsit CJSheinkopf SJDellaGrotta SACheck JNeal CRPastyrnak SHelderman JO'Shea MLester BMDansereau LMCarter BSHofheimer JASmith LMMcGowan ECManigault AWEverson TMfalseAcoustic Cry Characteristics in Preterm Infants and Developmental and Behavioral Outcomes at 2 Years of Age.<h4>Importance</h4>Acoustic cry characteristics have been associated with severe medical problems in newborns. However, little is known about the utility of neonatal acoustic cry characteristics in the prediction of long-term outcomes of very preterm infants.<h4>Objectives</h4>To evaluate whether acoustic characteristics of infant cry at neonatal intensive care unit (NICU) discharge are associated with behavioral and developmental outcomes at age 2 years in infants born very preterm.<h4>Design, setting, and participants</h4>Infants born less than 30 weeks postmenstrual age (PMA) were enrolled from April 2014 through June 2016 as part of a multicenter (9 US university affiliated NICUs) cohort study and followed to adjusted age 2 years. Reported analyses began on September 2021. Data were an2023-01-01T00:00:00Z2023 Feb2025-04-19T13:30:17.661Z2025-04-19T13:30:17.661ZS-EPMC98929563672394110.1001/jamanetworkopen.2022.54151