biostudies-literatureChen YYThe New Energy and Industrial Technology Development Organization16https://www.ebi.ac.uk/biostudies/studies/S-EPMC9893580biostudies-literatureUnknown16(1)<h4>Background</h4>Methane (CH₄), as one of the major energy sources, easily escapes from the supply chain into the atmosphere, because it exists in a gaseous state under ambient conditions. Compared to carbon dioxide (CO₂), CH₄ is 25 times more potent at trapping radiation; thus, the emission of CH₄ to the atmosphere causes severe global warming and climate change. To mitigate CH₄ emissions and utilize them effectively, the direct biological conversion of CH₄ into liquid fuels, such as methanol (CH₃OH), using methanotrophs is a promising strategy. However, supplying biocatalysts in an aqueous medium with CH₄ involves high energy consumption due to vigorous agitation and/or bubbling, which is a serious Biotechnology for biofuels and bioproductsA novel inverse membrane bioreactor for efficient bioconversion from methane gas to liquid methanol using a microbial gas-phase reaction.PMC9893580JPNP18016Ishikawa MHori KChen YYfalseA novel inverse membrane bioreactor for efficient bioconversion from methane gas to liquid methanol using a microbial gas-phase reaction.<h4>Background</h4>Methane (CH₄), as one of the major energy sources, easily escapes from the supply chain into the atmosphere, because it exists in a gaseous state under ambient conditions. Compared to carbon dioxide (CO₂), CH₄ is 25 times more potent at trapping radiation; thus, the emission of CH₄ to the atmosphere causes severe global warming and climate change. To mitigate CH₄ emissions and utilize them effectively, the direct biological conversion of CH₄ into liquid fuels, such as methanol (CH₃OH), using methanotrophs is a promising strategy. However, supplying biocatalysts in an aqueous medium with CH₄ involves high energy consumption due to vigorous agitation and/or bubbling, which is a serious 2023-01-01T00:00:00Z2023 Feb2025-05-29T19:45:30.79Z2025-04-06T15:44:11.444ZS-EPMC98935803673282510.1186/s13068-023-02267-6