{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18(2)"],"submitter":["Venegas-Rodriguez R"],"pubmed_abstract":["This paper presents the results of an observational and retrospective study on the therapeutic effects of Jusvinza, an immunomodulatory peptide with anti-inflammatory properties for critically ill COVID-19 patients. This peptide induces regulatory mechanisms on the immune response in experimental systems and in patients with Rheumatoid Arthritis. Exploratory research in COVID-19 patients revealed that Jusvinza promotes clinical and radiological improvement. The aim of this study is to describe the clinical outcome and variations of several inflammatory biomarkers in a cohort of critically ill COVID-19 patients, divided into two groups during the observational research: one group received Jusvinza and the other did not. Research physicians extracted the patients´ data from their hospital's "],"journal":["PloS one"],"pagination":["e0281111"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9894446"],"repository":["biostudies-literature"],"pubmed_title":["Jusvinza, an anti-inflammatory drug derived from the human heat-shock protein 60, for critically ill COVID-19 patients. An observational study."],"pmcid":["PMC9894446"],"pubmed_authors":["Rosario-Cruz L","Perez-Aguilera L","Dominguez-Horta MDC","Santana-Sanchez R","Venegas-Rodriguez R","Martinez-Donato G","Guillen-Nieto G","Pena-Ruiz R","Hernandez-Cedeno M","Grecesqui-Cruz I","Serrano-Diaz A","Rittoles Navarro A","Segura-Fernandez A"],"additional_accession":[]},"is_claimable":false,"name":"Jusvinza, an anti-inflammatory drug derived from the human heat-shock protein 60, for critically ill COVID-19 patients. An observational study.","description":"This paper presents the results of an observational and retrospective study on the therapeutic effects of Jusvinza, an immunomodulatory peptide with anti-inflammatory properties for critically ill COVID-19 patients. This peptide induces regulatory mechanisms on the immune response in experimental systems and in patients with Rheumatoid Arthritis. Exploratory research in COVID-19 patients revealed that Jusvinza promotes clinical and radiological improvement. The aim of this study is to describe the clinical outcome and variations of several inflammatory biomarkers in a cohort of critically ill COVID-19 patients, divided into two groups during the observational research: one group received Jusvinza and the other did not. Research physicians extracted the patients´ data from their hospital's ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-26T18:10:46.109Z","creation":"2025-04-06T15:43:12.97Z"},"accession":"S-EPMC9894446","cross_references":{"pubmed":["36730325"],"doi":["10.1371/journal.pone.0281111"]}}