{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang R"],"funding":["Key Research Program of the Chinese Academy of Sciences","Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China","National Natural Science Foundation of China"],"pagination":["e2205320"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9896051"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(4)"],"pubmed_abstract":["Rheumatoid arthritis (RA) is a common, chronic, and highly disabling autoimmune disease characterized by difficult treatment, long disease duration, and easy recurrence. The development and application of high-sensitivity theranostic probes for RA that will facilitate precise monitoring of disease progression and enable effective treatment are currently hotspots in the field of RA theranostics. In this study, mZMI@HA, a dual-triggered theranostics nanoprobe, is constructed based on near-infrared persistent luminescence nanoparticles (NIR-PLNPs) for precise RA treatment and therapeutic evaluation. This is the first reported use of high-sensitivity autofluorescence-free imaging based on NIR-PLNPs for precise RA treatment and therapeutic evaluation. Compared with the NIR fluorescence imaging "],"journal":["Advanced science (Weinheim, Baden-Wurttemberg, Germany)"],"pubmed_title":["Dual-Triggered Near-Infrared Persistent Luminescence Nanoprobe for Autofluorescence-Free Imaging-Guided Precise Therapy of Rheumatoid Arthritis."],"pmcid":["PMC9896051"],"funding_grant_id":["2020ZZ114 Z","62105333","ZDRW-CN-2021-3","61705228"],"pubmed_authors":["Song L","Wang R","Zhang Y","Peng Q","Shi J","Sun X","Zhang Q"],"additional_accession":[]},"is_claimable":false,"name":"Dual-Triggered Near-Infrared Persistent Luminescence Nanoprobe for Autofluorescence-Free Imaging-Guided Precise Therapy of Rheumatoid Arthritis.","description":"Rheumatoid arthritis (RA) is a common, chronic, and highly disabling autoimmune disease characterized by difficult treatment, long disease duration, and easy recurrence. The development and application of high-sensitivity theranostic probes for RA that will facilitate precise monitoring of disease progression and enable effective treatment are currently hotspots in the field of RA theranostics. In this study, mZMI@HA, a dual-triggered theranostics nanoprobe, is constructed based on near-infrared persistent luminescence nanoparticles (NIR-PLNPs) for precise RA treatment and therapeutic evaluation. This is the first reported use of high-sensitivity autofluorescence-free imaging based on NIR-PLNPs for precise RA treatment and therapeutic evaluation. Compared with the NIR fluorescence imaging ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-18T23:28:29.623Z","creation":"2025-04-07T11:03:05.411Z"},"accession":"S-EPMC9896051","cross_references":{"pubmed":["36461720"],"doi":["10.1002/advs.202205320"]}}