biostudies-literatureUnknown13(2)Wang W<h4>Introduction</h4>Human papillomavirus (HPV) infection is the most common sexually transmissible infection worldwide. Although the prevalence of cervical HPV infection has been extensively reported in women worldwide, few epidemiological studies have examined the prevalence of non-cervical HPV infection among both women and men, especially in China.<h4>Methods and analysis</h4>PROGRESS-Plus is a national, multisite, cross-sectional study that aims to estimate the prevalence of non-cervical HPV infection in women and men aged 18-60 years residing in mainland China. More specifically, PROGRESS-Plus will estimate the prevalence rate of HPV DNA in oral samples from both women and men, and that of anogenital samples from men. The secondary study objectives are to (1) report the aforementioneBMJ opene065749https://www.ebi.ac.uk/biostudies/studies/S-EPMC9896211biostudies-literatureEstimating the prevalence of non-cervical human papillomavirus infection in mainland China (PROGRESS-Plus): protocol of a national cross-sectional study.PMC9896211Qiao YRoberts CKothari-Talwar SPanchal RChen YTWang WCui FLu QLara NMorais EfalseEstimating the prevalence of non-cervical human papillomavirus infection in mainland China (PROGRESS-Plus): protocol of a national cross-sectional study.<h4>Introduction</h4>Human papillomavirus (HPV) infection is the most common sexually transmissible infection worldwide. Although the prevalence of cervical HPV infection has been extensively reported in women worldwide, few epidemiological studies have examined the prevalence of non-cervical HPV infection among both women and men, especially in China.<h4>Methods and analysis</h4>PROGRESS-Plus is a national, multisite, cross-sectional study that aims to estimate the prevalence of non-cervical HPV infection in women and men aged 18-60 years residing in mainland China. More specifically, PROGRESS-Plus will estimate the prevalence rate of HPV DNA in oral samples from both women and men, and that of anogenital samples from men. The secondary study objectives are to (1) report the aforementione2023-01-01T00:00:00Z2023 Feb2026-07-16T21:13:52.579Z2025-04-06T02:21:52.645ZS-EPMC98962113673192510.1136/bmjopen-2022-065749