{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(18)"],"submitter":["Gossl M"],"pubmed_abstract":["<h4>Background</h4>Treatment of mitral regurgitation (MR) associated with severe mitral annular calcification (MAC) is challenging due to the high risk of fatal atrioventricular groove disruption and significant paravalvular leak.<h4>Aims</h4>The aim of this study was to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) with the Tendyne valve (Abbott Structural) in patients with MR and MAC.<h4>Methods</h4>Twenty patients (mean age 78 years; 11 women) who were treated with the Tendyne valve, either compassionate use (CU; closed) or as part of The Feasibility Study of Tendyne in MAC (NCT03539458), had reported outcomes in a median follow-up duration of 368 days.<h4>Results</h4>In all patients, a valve was implanted with no procedural mortality and successful hospital dis"],"journal":["EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology"],"pagination":["1523-1531"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9896404"],"repository":["biostudies-literature"],"pubmed_title":["Early outcomes of transcatheter mitral valve replacement with the Tendyne system in severe mitral annular calcification."],"pmcid":["PMC9896404"],"pubmed_authors":["Sorajja P","Badhwar V","Conradi L","Sun B","Guyton R","Babaliaros V","Dumonteil N","Thourani V","Blanke P","Bae R","Chehab B","Rizik D","Gossl M","Chuang M"],"additional_accession":[]},"is_claimable":false,"name":"Early outcomes of transcatheter mitral valve replacement with the Tendyne system in severe mitral annular calcification.","description":"<h4>Background</h4>Treatment of mitral regurgitation (MR) associated with severe mitral annular calcification (MAC) is challenging due to the high risk of fatal atrioventricular groove disruption and significant paravalvular leak.<h4>Aims</h4>The aim of this study was to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) with the Tendyne valve (Abbott Structural) in patients with MR and MAC.<h4>Methods</h4>Twenty patients (mean age 78 years; 11 women) who were treated with the Tendyne valve, either compassionate use (CU; closed) or as part of The Feasibility Study of Tendyne in MAC (NCT03539458), had reported outcomes in a median follow-up duration of 368 days.<h4>Results</h4>In all patients, a valve was implanted with no procedural mortality and successful hospital dis","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-05-29T02:25:13.728Z","creation":"2025-02-19T04:16:00.989Z"},"accession":"S-EPMC9896404","cross_references":{"pubmed":["34918624"],"doi":["10.4244/EIJ-D-21-00745","10.4244/eij-d-21-00745"]}}