biostudies-literatureUnknown13Duan H<i>Salicornia europaea</i> is one of the world's salt-tolerant plant species and is recognized as a model plant for studying the metabolism and molecular mechanisms of halophytes under salinity. To investigate the metabolic responses to salinity stress in <i>S. europaea</i>, this study performed a widely targeted metabolomic analysis after analyzing the physiological characteristics of plants exposed to various NaCl treatments. <i>S. europaea</i> exhibited excellent salt tolerance and could withstand extremely high NaCl concentrations, while lower NaCl conditions (50 and 100 mM) significantly promoted growth by increasing tissue succulence and maintaining a relatively stable K⁺ concentration. A total of 552 metabolites were detected, 500 of which were differently accumulated, maFrontiers in plant science1097076https://www.ebi.ac.uk/biostudies/studies/S-EPMC9896792biostudies-literatureMetabolomics analysis unveils important changes involved in the salt tolerance of <i>Salicornia europaea</i>.PMC9896792Tiika RJYang HTian FHu YLu YCui GDuan HZhang QfalseMetabolomics analysis unveils important changes involved in the salt tolerance of <i>Salicornia europaea</i>.<i>Salicornia europaea</i> is one of the world's salt-tolerant plant species and is recognized as a model plant for studying the metabolism and molecular mechanisms of halophytes under salinity. To investigate the metabolic responses to salinity stress in <i>S. europaea</i>, this study performed a widely targeted metabolomic analysis after analyzing the physiological characteristics of plants exposed to various NaCl treatments. <i>S. europaea</i> exhibited excellent salt tolerance and could withstand extremely high NaCl concentrations, while lower NaCl conditions (50 and 100 mM) significantly promoted growth by increasing tissue succulence and maintaining a relatively stable K⁺ concentration. A total of 552 metabolites were detected, 500 of which were differently accumulated, ma2022-01-01T00:00:00Z20222025-04-05T13:30:57.387Z2025-04-05T13:30:57.387ZS-EPMC98967923674353610.3389/fpls.2022.1097076