biostudies-literatureXiong CChinese Academy of Medical Sciences Central Public Welfare Scientific Research Institute Basal Research Expenses—Clinical and Translational Medicine Research Fund2170244https://www.ebi.ac.uk/biostudies/studies/S-EPMC9897740biostudies-literatureUnknown45(1)<h4>Introduction</h4>Dysmagnesemia has been demonstrated to be involved in the pathophysiology of kidney diseases and is common in cardiac surgical patients. It remains unknown whether changes of serum magnesium after cardiac surgery affect AKI. We aimed to investigate the association of early postoperative magnesium with cardiac surgery-associated AKI in adults.<h4>Methods</h4>We conducted a multicenter retrospective cohort study involving patients who underwent cardiac surgery in the eICU Collaborative Research Database between 2014 and 2015. AKI within 7 days after surgery was defined using both serum creatinine and urine output criteria of Kidney Disease Improving Global Outcomes definition. Postoperative AKI was analyzed using multivariable logistic regression with early postoperativeRenal failureAssociation of early postoperative serum magnesium with acute kidney injury after cardiac surgery.PMC98977402021-I2M-C&amp;T-B-036Cao LTian LShi SZeng MJia YXiong CWang HWang JfalseAssociation of early postoperative serum magnesium with acute kidney injury after cardiac surgery.<h4>Introduction</h4>Dysmagnesemia has been demonstrated to be involved in the pathophysiology of kidney diseases and is common in cardiac surgical patients. It remains unknown whether changes of serum magnesium after cardiac surgery affect AKI. We aimed to investigate the association of early postoperative magnesium with cardiac surgery-associated AKI in adults.<h4>Methods</h4>We conducted a multicenter retrospective cohort study involving patients who underwent cardiac surgery in the eICU Collaborative Research Database between 2014 and 2015. AKI within 7 days after surgery was defined using both serum creatinine and urine output criteria of Kidney Disease Improving Global Outcomes definition. Postoperative AKI was analyzed using multivariable logistic regression with early postoperative2023-01-01T00:00:00Z2023 Dec2025-04-05T13:31:26.931Z2025-04-05T13:31:26.931ZS-EPMC98977403672871110.1080/0886022X.2023.2170244