{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28(1)"],"submitter":["Andrews N"],"pubmed_abstract":["<h4>Objective</h4>This study is to evaluate the effects of darbepoetin alfa (darbe) on neutrophil count in preterm neonates treated for anemia of prematurity.<h4>Methods</h4>This was a retrospective chart review comparing the absolute neutrophil counts (ANCs) of neonates administered 2 doses of subcutaneous darbe 10 mcg/kg to that of a randomly selected comparator group of neonates not administered the drug. Neonates <34 weeks gestational age, gestational age between 23w1d and 33w4d, born between July 2016 and June 2019, were included in the study.<h4>Results</h4>The ANCs of 45 darbe-treated neonates compared with those of 45 randomly selected comparator control neonates revealed no difference in the rate of occurrence of neutropenia (ANC ≤1000/μL) between the darbe-treated neonates (26.7%"],"journal":["The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG"],"pagination":["41-47"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9901317"],"repository":["biostudies-literature"],"pubmed_title":["Characterization of Neutropenia in Preterm Neonates Following Administration of Darbepoetin Alfa."],"pmcid":["PMC9901317"],"pubmed_authors":["Friedman S","Dunham M","Andrews N","Dean R","Chabra S"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of Neutropenia in Preterm Neonates Following Administration of Darbepoetin Alfa.","description":"<h4>Objective</h4>This study is to evaluate the effects of darbepoetin alfa (darbe) on neutrophil count in preterm neonates treated for anemia of prematurity.<h4>Methods</h4>This was a retrospective chart review comparing the absolute neutrophil counts (ANCs) of neonates administered 2 doses of subcutaneous darbe 10 mcg/kg to that of a randomly selected comparator group of neonates not administered the drug. Neonates <34 weeks gestational age, gestational age between 23w1d and 33w4d, born between July 2016 and June 2019, were included in the study.<h4>Results</h4>The ANCs of 45 darbe-treated neonates compared with those of 45 randomly selected comparator control neonates revealed no difference in the rate of occurrence of neutropenia (ANC ≤1000/μL) between the darbe-treated neonates (26.7%","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-25T19:19:07.86Z","creation":"2025-04-06T07:57:46.05Z"},"accession":"S-EPMC9901317","cross_references":{"pubmed":["36777988"],"doi":["10.5863/1551-6776-28.1.41"]}}