biostudies-literatureUnknown28(1)Andrews N<h4>Objective</h4>This study is to evaluate the effects of darbepoetin alfa (darbe) on neutrophil count in preterm neonates treated for anemia of prematurity.<h4>Methods</h4>This was a retrospective chart review comparing the absolute neutrophil counts (ANCs) of neonates administered 2 doses of subcutaneous darbe 10 mcg/kg to that of a randomly selected comparator group of neonates not administered the drug. Neonates <34 weeks gestational age, gestational age between 23w1d and 33w4d, born between July 2016 and June 2019, were included in the study.<h4>Results</h4>The ANCs of 45 darbe-treated neonates compared with those of 45 randomly selected comparator control neonates revealed no difference in the rate of occurrence of neutropenia (ANC ≤1000/μL) between the darbe-treated neonates (26.7%The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG41-47https://www.ebi.ac.uk/biostudies/studies/S-EPMC9901317biostudies-literatureCharacterization of Neutropenia in Preterm Neonates Following Administration of Darbepoetin Alfa.PMC9901317Friedman SDunham MAndrews NDean RChabra SfalseCharacterization of Neutropenia in Preterm Neonates Following Administration of Darbepoetin Alfa.<h4>Objective</h4>This study is to evaluate the effects of darbepoetin alfa (darbe) on neutrophil count in preterm neonates treated for anemia of prematurity.<h4>Methods</h4>This was a retrospective chart review comparing the absolute neutrophil counts (ANCs) of neonates administered 2 doses of subcutaneous darbe 10 mcg/kg to that of a randomly selected comparator group of neonates not administered the drug. Neonates <34 weeks gestational age, gestational age between 23w1d and 33w4d, born between July 2016 and June 2019, were included in the study.<h4>Results</h4>The ANCs of 45 darbe-treated neonates compared with those of 45 randomly selected comparator control neonates revealed no difference in the rate of occurrence of neutropenia (ANC ≤1000/μL) between the darbe-treated neonates (26.7%2023-01-01T00:00:00Z20232025-04-25T19:19:07.86Z2025-04-06T07:57:46.05ZS-EPMC99013173677798810.5863/1551-6776-28.1.41