{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Neuenschwander S"],"funding":["Novo Nordisk Foundation","Swiss National Science Foundation","Novo Nordisk Foundation Center for Protein Research"],"pagination":["btad028"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9901408"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["39(2)"],"pubmed_abstract":["<h4>Summary</h4>We introduce mapache, a flexible, robust and scalable pipeline to map, quantify and impute ancient and present-day DNA in a reproducible way. Mapache is implemented in the workflow manager Snakemake and is optimized for low-space consumption, allowing to efficiently (re)map large datasets-such as reference panels and multiple extracts and libraries per sample - to one or several genomes. Mapache can easily be customized or combined with other Snakemake tools.<h4>Availability and implementation</h4>Mapache is freely available on GitHub (https://github.com/sneuensc/mapache). An extensive manual is provided at https://github.com/sneuensc/mapache/wiki.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online."],"journal":["Bioinformatics (Oxford, England)"],"pubmed_title":["Mapache: a flexible pipeline to map ancient DNA."],"pmcid":["PMC9901408"],"funding_grant_id":["PCEGP3_181251","PI Simon Rasmussen","181251"],"pubmed_authors":["Sousa da Mota B","Neuenschwander S","Bozzi D","Rasmussen S","Anchieri L","Rubinacci S","Cruz Davalos DI","Malaspinas AS","Delaneau O"],"additional_accession":[]},"is_claimable":false,"name":"Mapache: a flexible pipeline to map ancient DNA.","description":"<h4>Summary</h4>We introduce mapache, a flexible, robust and scalable pipeline to map, quantify and impute ancient and present-day DNA in a reproducible way. Mapache is implemented in the workflow manager Snakemake and is optimized for low-space consumption, allowing to efficiently (re)map large datasets-such as reference panels and multiple extracts and libraries per sample - to one or several genomes. Mapache can easily be customized or combined with other Snakemake tools.<h4>Availability and implementation</h4>Mapache is freely available on GitHub (https://github.com/sneuensc/mapache). An extensive manual is provided at https://github.com/sneuensc/mapache/wiki.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-04-07T13:36:11.771Z","creation":"2025-02-19T00:12:18.243Z"},"accession":"S-EPMC9901408","cross_references":{"pubmed":["36637197"],"doi":["10.1093/bioinformatics/btad028"]}}