{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(1)"],"submitter":["Xin JX"],"funding":["Microscale Magnetic Resonance Platform of ECNU","Xing-Fu-Zhi-Hua Foundation of ECNU"],"pubmed_abstract":["Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have made great successes in clinical diagnosis, medical research, and neurological science. MRI provides high resolution anatomical images of tissues/organs, and MRS provides information of the functional molecules related to a specific tissue/organ. However, it is difficult for classic MRI/MRS to selectively image/probe a specific metabolite molecule other than the water or fat in tissues/organs. This greatly limits their applications on the study of the molecular mechanism(s) of metabolism and disease. Herein, we report a series of molecularly targeted MRI/MRS methods to target specific molecules. The optimal control method was used to efficiently prepare the singlet spin orders of varied multi-spin systems and i"],"journal":["Scientific reports"],"pagination":["2212"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9905495"],"repository":["biostudies-literature"],"pubmed_title":["Using optimal controlled singlet spin order to accurately target molecular signal in MRI and MRS."],"pmcid":["PMC9905495"],"pubmed_authors":["Tong R","Yang G","Li J","Fu C","Xin JX","Zhang H","Ren Y","Wei DX","Wang J","Yao YF"],"additional_accession":[]},"is_claimable":false,"name":"Using optimal controlled singlet spin order to accurately target molecular signal in MRI and MRS.","description":"Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have made great successes in clinical diagnosis, medical research, and neurological science. MRI provides high resolution anatomical images of tissues/organs, and MRS provides information of the functional molecules related to a specific tissue/organ. However, it is difficult for classic MRI/MRS to selectively image/probe a specific metabolite molecule other than the water or fat in tissues/organs. This greatly limits their applications on the study of the molecular mechanism(s) of metabolism and disease. Herein, we report a series of molecularly targeted MRI/MRS methods to target specific molecules. The optimal control method was used to efficiently prepare the singlet spin orders of varied multi-spin systems and i","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-18T20:47:58.391Z","creation":"2025-04-07T08:47:40.683Z"},"accession":"S-EPMC9905495","cross_references":{"pubmed":["36750607"],"doi":["10.1038/s41598-023-28425-2"]}}