biostudies-literatureUnknown13Tian F<h4>Background</h4>Laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) has increased. However, the long-term outcomes of LLR for HCCs should be validated further. Besides, the validity of laparoscopic minor liver resection in difficult segments (1, 4a, 7, 8) (LMLR-DS) and laparoscopic major hepatectomy (LMH) for HCCs need to be studied.<h4>Methods</h4>A total of 1773 HCC patients were collected: 683 received LLR and 1090 received OLR. Propensity score matching (PSM) with 1:1 ratio was used to eliminate the selection bias. Short-term and long-term outcomes were compared. In subgroup analyses, the validity of LMLR-DS or LMH for HCCs was studied.<h4>Results</h4>After PSM, 567 patients were in LLR or OLR group. LLR had lower intraoperative blood-loss and shorter postoperativeFrontiers in oncology1112380https://www.ebi.ac.uk/biostudies/studies/S-EPMC9905741biostudies-literatureLong-term outcomes of laparoscopic liver resection versus open liver resection for hepatocellular carcinoma: A single-center 10-year experience.PMC9905741Cao LLi XLi JTian FChen JLeng SCao YZheng SWang XWang JfalseLong-term outcomes of laparoscopic liver resection versus open liver resection for hepatocellular carcinoma: A single-center 10-year experience.<h4>Background</h4>Laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) has increased. However, the long-term outcomes of LLR for HCCs should be validated further. Besides, the validity of laparoscopic minor liver resection in difficult segments (1, 4a, 7, 8) (LMLR-DS) and laparoscopic major hepatectomy (LMH) for HCCs need to be studied.<h4>Methods</h4>A total of 1773 HCC patients were collected: 683 received LLR and 1090 received OLR. Propensity score matching (PSM) with 1:1 ratio was used to eliminate the selection bias. Short-term and long-term outcomes were compared. In subgroup analyses, the validity of LMLR-DS or LMH for HCCs was studied.<h4>Results</h4>After PSM, 567 patients were in LLR or OLR group. LLR had lower intraoperative blood-loss and shorter postoperative2023-01-01T00:00:00Z20232025-04-04T18:44:10.626Z2025-04-04T18:44:10.626ZS-EPMC99057413676197810.3389/fonc.2023.1112380