biostudies-literatureNtinginya NEBundesministerium für Bildung und ForschungGerman Ministry of Education and Research;European & Developing Countries Clinical Trials Partnership (EDCTP)NIAID NIH HHSe990-e994https://www.ebi.ac.uk/biostudies/studies/S-EPMC9907486biostudies-literatureUnknown76(3)Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.Clinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaTuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse.PMC9907486UM1 AI068634Boeree MJHeinrich NBakuli AReither KHoelscher MSabiiti WKibiki GKuchaka DNtinginya NEPan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) ConsortiumGillespie SHMapamba DMinja LTPhillips PPJfalseTuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse.Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.2023-01-01T00:00:00Z2023 Feb2026-05-28T18:36:29.488Z2025-04-19T02:46:50.54ZS-EPMC99074863571764310.1093/cid/ciac445