biostudies-literatureUnknown10Wang Z<h4>Introduction</h4>Polygonati Rhizoma is a multi-purpose food with medicinal uses. Fermentation of Polygonati Rhizoma by lactic acid bacteria could provide new insights into the development of Polygonati Rhizoma products.<h4>Methods</h4>In this study, <i>Lactiplantibacillus plantarum</i> was fermented with Polygonati Rhizoma extracts in a bioreactor under aerobic and anaerobic conditions with pH and DO real-time detection. Metabolic profiling was determined by UHPLC-QE-MS/MS system. Principal component analysis and orthogonal partial least-squares discriminant analysis were used to perform multivariate analysis.<h4>Results</h4>A total of 98 differential metabolites were identified in broth after fermentation, and 36 were identified between fermentation under aerobic and anaerobic conditiFrontiers in nutrition1093761https://www.ebi.ac.uk/biostudies/studies/S-EPMC9908587biostudies-literatureInsights into the metabolic profiling of Polygonati Rhizoma fermented by <i>Lactiplantibacillus plantarum</i> under aerobic and anaerobic conditions using a UHPLC-QE-MS/MS system.PMC9908587Liu XKang XZhong CHe WXie ZLao JZhang SWang ZJin JfalseInsights into the metabolic profiling of Polygonati Rhizoma fermented by <i>Lactiplantibacillus plantarum</i> under aerobic and anaerobic conditions using a UHPLC-QE-MS/MS system.<h4>Introduction</h4>Polygonati Rhizoma is a multi-purpose food with medicinal uses. Fermentation of Polygonati Rhizoma by lactic acid bacteria could provide new insights into the development of Polygonati Rhizoma products.<h4>Methods</h4>In this study, <i>Lactiplantibacillus plantarum</i> was fermented with Polygonati Rhizoma extracts in a bioreactor under aerobic and anaerobic conditions with pH and DO real-time detection. Metabolic profiling was determined by UHPLC-QE-MS/MS system. Principal component analysis and orthogonal partial least-squares discriminant analysis were used to perform multivariate analysis.<h4>Results</h4>A total of 98 differential metabolites were identified in broth after fermentation, and 36 were identified between fermentation under aerobic and anaerobic conditi2023-01-01T00:00:00Z20232025-05-29T21:47:54.399Z2025-05-29T21:47:54.399ZS-EPMC99085873677661210.3389/fnut.2023.1093761