biostudies-literatureUnknown26(1)Hamblin R<h4>Purpose</h4>The optimal management approach for presumed non-functioning pituitary microadenomas (microNFPAs) remains unclear. Our aim was to capture current UK practice and identify changes with time.<h4>Methods</h4>Two online surveys investigating clinicians' approaches were performed in 2009-2010 and 2021-2022 (advertised through Society for Endocrinology UK).<h4>Results</h4>150 and 214 clinicians participated in the 2021 and 2009 survey, respectively (response rates 31.2% and 35.4%, respectively). At baseline, 2021 survey respondents were more likely to measure IGF-1 (96.0% vs 74.1%, p < 0.001) and morning cortisol (87.9% vs 62.6%, p < 0.001), and less likely GH (26.2% vs 42.6% p = 0.002), 24 h urine free cortisol (3.4% vs 23.2%, p < 0.0001) or dynamically assess adrenal reserve (1Pituitary94-104https://www.ebi.ac.uk/biostudies/studies/S-EPMC9908737biostudies-literatureUK practice on incidentally detected non-functioning pituitary microadenomas: analysis of two national surveys during a 12-year interval.PMC9908737Fountas AHamblin RKaravitaki NLevy MfalseUK practice on incidentally detected non-functioning pituitary microadenomas: analysis of two national surveys during a 12-year interval.<h4>Purpose</h4>The optimal management approach for presumed non-functioning pituitary microadenomas (microNFPAs) remains unclear. Our aim was to capture current UK practice and identify changes with time.<h4>Methods</h4>Two online surveys investigating clinicians' approaches were performed in 2009-2010 and 2021-2022 (advertised through Society for Endocrinology UK).<h4>Results</h4>150 and 214 clinicians participated in the 2021 and 2009 survey, respectively (response rates 31.2% and 35.4%, respectively). At baseline, 2021 survey respondents were more likely to measure IGF-1 (96.0% vs 74.1%, p < 0.001) and morning cortisol (87.9% vs 62.6%, p < 0.001), and less likely GH (26.2% vs 42.6% p = 0.002), 24 h urine free cortisol (3.4% vs 23.2%, p < 0.0001) or dynamically assess adrenal reserve (12023-01-01T00:00:00Z2023 Feb2025-04-21T22:45:10.485Z2025-04-05T18:52:59.888ZS-EPMC99087373643429310.1007/s11102-022-01290-4