{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["401(10375)"],"submitter":["Villar J"],"pubmed_abstract":["<h4>Background</h4>In 2021, we showed an increased risk associated with COVID-19 in pregnancy. Since then, the SARS-CoV-2 virus has undergone genetic mutations. We aimed to examine the effects on maternal and perinatal outcomes of COVID-19 during pregnancy, and evaluate vaccine effectiveness, when omicron (B.1.1.529) was the variant of concern.<h4>Methods</h4>INTERCOVID-2022 is a large, prospective, observational study, involving 41 hospitals across 18 countries. Each woman with real-time PCR or rapid test, laboratory-confirmed COVID-19 in pregnancy was compared with two unmatched women without a COVID-19 diagnosis who were recruited concomitantly and consecutively in pregnancy or at delivery. Mother and neonate dyads were followed until hospital discharge. Primary outcomes were maternal m"],"journal":["Lancet (London, England)"],"pagination":["447-457"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9910845"],"repository":["biostudies-literature"],"pubmed_title":["Pregnancy outcomes and vaccine effectiveness during the period of omicron as the variant of concern, INTERCOVID-2022: a multinational, observational study."],"pmcid":["PMC9910845"],"pubmed_authors":["Tavchioska G","Savasi V","Papageorghiou AT","Ernawati E","Bhutta ZA","Napolitano R","Fabre M","Gunier RB","Salomon LJ","Marler E","Winsey A","Hubka T","Casale RA","Peterson A","Eskenazi B","INTERCOVID-2022 International Consortium","Teji JS","Deantoni S","Caceres DM","Gandino S","Rauch S","Cavoretto PI","Lipschuetz M","Vecchiarelli C","Ayede AI","Maiz N","Rodriguez GB","Thornton JG","Tug N","Deruelle P","Capelli C","Soto Conti CP","Bako B","Nieto R","Gravett MG","Villar J","Easter SR","Craik R","Giudice C","Ikenoue S","Menis C","Takahashi K","Ariff S","Hernandez V","Livio S","Prefumo F","Kennedy SH","Sentilhes L","Albornoz Crespo G","Rodriguez-Sibaja MJ","Vale M","Martinez de Tejada B","Sobrero H","Cheikh Ismail L"],"additional_accession":[]},"is_claimable":false,"name":"Pregnancy outcomes and vaccine effectiveness during the period of omicron as the variant of concern, INTERCOVID-2022: a multinational, observational study.","description":"<h4>Background</h4>In 2021, we showed an increased risk associated with COVID-19 in pregnancy. Since then, the SARS-CoV-2 virus has undergone genetic mutations. We aimed to examine the effects on maternal and perinatal outcomes of COVID-19 during pregnancy, and evaluate vaccine effectiveness, when omicron (B.1.1.529) was the variant of concern.<h4>Methods</h4>INTERCOVID-2022 is a large, prospective, observational study, involving 41 hospitals across 18 countries. Each woman with real-time PCR or rapid test, laboratory-confirmed COVID-19 in pregnancy was compared with two unmatched women without a COVID-19 diagnosis who were recruited concomitantly and consecutively in pregnancy or at delivery. Mother and neonate dyads were followed until hospital discharge. Primary outcomes were maternal m","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-03-16T08:12:18.148Z","creation":"2024-11-08T14:00:23.443Z"},"accession":"S-EPMC9910845","cross_references":{"pubmed":["36669520"],"doi":["10.1016/S0140-6736(22)02467-9"]}}