biostudies-literatureKwizera AWellcome Trust369-380https://www.ebi.ac.uk/biostudies/studies/S-EPMC9911971biostudies-literatureUnknown164(2)<h4>Background</h4>Limited data from low-income countries report on respiratory support techniques in COVID-19-associated ARDS.<h4>Research question</h4>Which respiratory support techniques are used in patients with COVID-19-associated ARDS in Uganda?<h4>Study design and methods</h4>A multicenter, prospective, observational study was conducted at 13 Ugandan hospitals during the pandemic and included adults with COVID-19-associated ARDS. Patient characteristics, clinical and laboratory data, initial and most advanced respiratory support techniques, and 28-day mortality were recorded. Standard tests, log-rank tests, and logistic regression analyses were used for statistical analyses.<h4>Results</h4>Four hundred ninety-nine patients with COVID-19-associated ARDS (mild, n = 137; moderate, n = ChestRespiratory Support Techniques for COVID-19-Related ARDS in a Sub-Saharan African Country: A Multicenter Observational Study.PMC9911971107742/Z/15/ZTumukunde JOlaro CKwizera ADunser MWSummers COwachi DKyobe-Bosa HKiwanuka NKabatooro DKateete DPSendagire CObua DMwanje AKNakiyingi LKirenga BJJoloba MAtumanya PNakibuuka JSewankambo NAgaba PAlenyo-Ngabirano AKalungi JfalseRespiratory Support Techniques for COVID-19-Related ARDS in a Sub-Saharan African Country: A Multicenter Observational Study.<h4>Background</h4>Limited data from low-income countries report on respiratory support techniques in COVID-19-associated ARDS.<h4>Research question</h4>Which respiratory support techniques are used in patients with COVID-19-associated ARDS in Uganda?<h4>Study design and methods</h4>A multicenter, prospective, observational study was conducted at 13 Ugandan hospitals during the pandemic and included adults with COVID-19-associated ARDS. Patient characteristics, clinical and laboratory data, initial and most advanced respiratory support techniques, and 28-day mortality were recorded. Standard tests, log-rank tests, and logistic regression analyses were used for statistical analyses.<h4>Results</h4>Four hundred ninety-nine patients with COVID-19-associated ARDS (mild, n = 137; moderate, n = 2023-01-01T00:00:00Z2023 Aug2025-04-04T13:07:35.788Z2025-04-04T13:07:35.788ZS-EPMC99119713677393310.1016/j.chest.2023.01.039