biostudies-literatureYennawar HPNational Institutes of Health, SIG S10NCRR NIH HHSNIH HHSNational Science Foundation120-123https://www.ebi.ac.uk/biostudies/studies/S-EPMC9912464biostudies-literatureUnknown79(Pt 2)The syntheses and crystal structures of two thia-zinone compounds, namely, <i>rac</i>-2,3-diphenyl-2,3,5,6-tetra-hydro-4<i>H</i>-1,3-thia-zine-1,1,4-trione, C₁₆H₁₅NO₃S, in its racemic form, and <i>N</i>-[(2<i>S</i>,5<i>R</i>)-1,1,4-trioxo-2,3-diphenyl-1,3-thia-zinan-5-yl]acet-amide, C₁₈H₁₈N₂O₄S, in an enanti-opure form, are reported. The thia-zine rings in the two structures differ in their puckering, as a half-chair in the first and a boat pucker in the second. The extended structures for both compounds have only C-H⋯O-type inter-actions between symmetry-related mol-ecules, and exhibit no π-π stacking inter-actions in spite of each having two phenyl rings.Acta crystallographica. Section E, Crystallographic communicationsCrystal structures of <i>rac</i>-2,3-diphenyl-2,3,5,6-tetra-hydro-4<i>H</i>-1,3-thia-zine-1,1,4-trione and <i>N</i>-[(2<i>S</i>,5<i>R</i>)-1,1,4-trioxo-2,3-diphenyl-1,3-thia-zinan-5-yl]acet-amide.PMC9912464S10 RR0234391S10RR023439–01CHEM-0131112S10 OD0285891S10OD028589–01Mammen MMLowe SLYennawar HPVerhagen CRSilverberg LJfalseCrystal structures of <i>rac</i>-2,3-diphenyl-2,3,5,6-tetra-hydro-4<i>H</i>-1,3-thia-zine-1,1,4-trione and <i>N</i>-[(2<i>S</i>,5<i>R</i>)-1,1,4-trioxo-2,3-diphenyl-1,3-thia-zinan-5-yl]acet-amide.The syntheses and crystal structures of two thia-zinone compounds, namely, <i>rac</i>-2,3-diphenyl-2,3,5,6-tetra-hydro-4<i>H</i>-1,3-thia-zine-1,1,4-trione, C₁₆H₁₅NO₃S, in its racemic form, and <i>N</i>-[(2<i>S</i>,5<i>R</i>)-1,1,4-trioxo-2,3-diphenyl-1,3-thia-zinan-5-yl]acet-amide, C₁₈H₁₈N₂O₄S, in an enanti-opure form, are reported. The thia-zine rings in the two structures differ in their puckering, as a half-chair in the first and a boat pucker in the second. The extended structures for both compounds have only C-H⋯O-type inter-actions between symmetry-related mol-ecules, and exhibit no π-π stacking inter-actions in spite of each having two phenyl rings.2023-01-01T00:00:00Z2023 Jan2025-08-13T03:04:30.787Z2025-04-04T11:17:14.021ZS-EPMC99124643679341010.1107/S2056989023000695