{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Diaz-Valenzuela E"],"pubmed_abstract":["<h4>Background</h4>Plant domestication is a remarkable example of rapid phenotypic transformation of polygenic traits, such as organ size. Evidence from a handful of study cases suggests this transformation is due to gene regulatory changes that result in non-additive phenotypes. Employing data from published genetic crosses, we estimated the role of non-additive gene action in the modulation of transcriptional landscapes in three domesticated plants: maize, sunflower, and chili pepper. Using A. thaliana, we assessed the correlation between gene regulatory network (GRN) connectivity properties, transcript abundance variation, and gene action. Finally, we investigated the propagation of non-additive gene action in GRNs.<h4>Results</h4>We compared crosses between domesticated plants and thei"],"journal":["EvoDevo"],"pagination":["3"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9912502"],"repository":["biostudies-literature"],"pubmed_title":["The role of non-additive gene action on gene expression variation in plant domestication."],"pmcid":["PMC9912502"],"pubmed_authors":["Hernandez-Rios D","Diaz-Valenzuela E","Cibrian-Jaramillo A"],"additional_accession":[]},"is_claimable":false,"name":"The role of non-additive gene action on gene expression variation in plant domestication.","description":"<h4>Background</h4>Plant domestication is a remarkable example of rapid phenotypic transformation of polygenic traits, such as organ size. Evidence from a handful of study cases suggests this transformation is due to gene regulatory changes that result in non-additive phenotypes. Employing data from published genetic crosses, we estimated the role of non-additive gene action in the modulation of transcriptional landscapes in three domesticated plants: maize, sunflower, and chili pepper. Using A. thaliana, we assessed the correlation between gene regulatory network (GRN) connectivity properties, transcript abundance variation, and gene action. Finally, we investigated the propagation of non-additive gene action in GRNs.<h4>Results</h4>We compared crosses between domesticated plants and thei","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-05-28T13:56:28.917Z","creation":"2024-11-20T02:07:01.071Z"},"accession":"S-EPMC9912502","cross_references":{"pubmed":["36765382"],"doi":["10.1186/s13227-022-00206-4"]}}