<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Tate DF</submitter><funding>NIDDK NIH HHS</funding><funding>National Institute of Diabetes and Digestive and Kidney Diseases</funding><pagination>2363-2375</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC9912959</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>30(12)</volume><pubmed_abstract>&lt;h4>Objective&lt;/h4>Despite the high prevalence of obesity and associated health risks in the United States adult population, few primary care providers (PCPs) have time and training to provide weight-management counseling to their patients. This study aims to compare the effect of referral to a comprehensive automated digital weight-loss program, with or without provider email feedback, with usual care on weight loss in patients with overweight or obesity.&lt;h4>Methods&lt;/h4>A total of 550 adults (mean [SD], 51.4 [11.2] years, BMI = 35.1 [5.5] kg/m&lt;sup>2&lt;/sup> , 72.0% female) were enrolled through their PCPs (n = 31). Providers were randomly assigned to refer their patients to a 12-month internet weight-loss intervention only (IWL), the intervention plus semiautomated feedback from the provider (IWL + PCP), or to usual care (EUC). Weight was measured at baseline and at 3, 6, and 12 months.&lt;h4>Results&lt;/h4>Weight changes (mean [SE]) at 12 months were -0.92 (0.46), -3.68 (0.46), and -3.58 (0.48) kg in the EUC, IWL, and IWL + PCP groups, respectively. Outcomes were significantly different in EUC versus IWL and EUC versus IWL + PCP (p &lt; 0.001), but not in IWL versus IWL + PCP.&lt;h4>Conclusions&lt;/h4>Referral by PCPs to an automated weight-loss program holds promise for patients with obesity. Future research should explore ways to further promote accountability and adherence.</pubmed_abstract><journal>Obesity (Silver Spring, Md.)</journal><pubmed_title>A cluster-randomized controlled trial of automated internet weight-loss programs in primary care: Role of automated provider feedback.</pubmed_title><pmcid>PMC9912959</pmcid><funding_grant_id>P30 DK056350</funding_grant_id><funding_grant_id>R01 DK095078</funding_grant_id><funding_grant_id>R01‐DK095078</funding_grant_id><pubmed_authors>Diamond M</pubmed_authors><pubmed_authors>Veldheer S</pubmed_authors><pubmed_authors>Hwang KO</pubmed_authors><pubmed_authors>Sciamanna CN</pubmed_authors><pubmed_authors>Tate DF</pubmed_authors><pubmed_authors>Kraschnewski JL</pubmed_authors><pubmed_authors>Martinez C</pubmed_authors><pubmed_authors>Lehman EB</pubmed_authors><pubmed_authors>Yang C</pubmed_authors></additional><is_claimable>false</is_claimable><name>A cluster-randomized controlled trial of automated internet weight-loss programs in primary care: Role of automated provider feedback.</name><description>&lt;h4>Objective&lt;/h4>Despite the high prevalence of obesity and associated health risks in the United States adult population, few primary care providers (PCPs) have time and training to provide weight-management counseling to their patients. This study aims to compare the effect of referral to a comprehensive automated digital weight-loss program, with or without provider email feedback, with usual care on weight loss in patients with overweight or obesity.&lt;h4>Methods&lt;/h4>A total of 550 adults (mean [SD], 51.4 [11.2] years, BMI = 35.1 [5.5] kg/m&lt;sup>2&lt;/sup> , 72.0% female) were enrolled through their PCPs (n = 31). Providers were randomly assigned to refer their patients to a 12-month internet weight-loss intervention only (IWL), the intervention plus semiautomated feedback from the provider (IWL + PCP), or to usual care (EUC). Weight was measured at baseline and at 3, 6, and 12 months.&lt;h4>Results&lt;/h4>Weight changes (mean [SE]) at 12 months were -0.92 (0.46), -3.68 (0.46), and -3.58 (0.48) kg in the EUC, IWL, and IWL + PCP groups, respectively. Outcomes were significantly different in EUC versus IWL and EUC versus IWL + PCP (p &lt; 0.001), but not in IWL versus IWL + PCP.&lt;h4>Conclusions&lt;/h4>Referral by PCPs to an automated weight-loss program holds promise for patients with obesity. Future research should explore ways to further promote accountability and adherence.</description><dates><release>2022-01-01T00:00:00Z</release><publication>2022 Dec</publication><modification>2026-05-29T07:38:14.646Z</modification><creation>2025-02-19T01:16:20.457Z</creation></dates><accession>S-EPMC9912959</accession><cross_references><pubmed>36416000</pubmed><doi>10.1002/oby.23506</doi></cross_references></HashMap>