biostudies-literatureGryczynski JNIDCR NIH HHSNational Institute of Dental and Craniofacial Research5https://www.ebi.ac.uk/biostudies/studies/S-EPMC9913004biostudies-literatureUnknown18(1)<h4>Background</h4>Opioid pain relievers are commonly prescribed following dental extractions, but evidence shows that non-opioid analgesics often provide adequate pain relief with fewer risks. The current study examined clinical decision support (CDS) as a tool for de-implementing opioid prescribing in dentistry.<h4>Methods</h4>This prospective, cluster-randomized trial examined CDS for dental pain management at 22 HealthPartners Dental Group clinics in Minnesota. Dental providers (n = 49) were randomized to deliver care using CDS, CDS with patient education materials (CDS-E), or standard practice (SP). Randomization was stratified by provider type (dentist vs. oral surgeon) and baseline opioid prescribing volume. Patient records of dental extractions were examined for January 2019 througImplementation science : ISDe-Implementing Opioids for Dental Extractions (DIODE): a multi-clinic, cluster-randomized trial of clinical decision support strategies in dentistry.PMC9913004U01DE027441U01 DE027441Asche SEWorley DCGryczynski JTruitt ARRindal DBMitchell SGfalseDe-Implementing Opioids for Dental Extractions (DIODE): a multi-clinic, cluster-randomized trial of clinical decision support strategies in dentistry.<h4>Background</h4>Opioid pain relievers are commonly prescribed following dental extractions, but evidence shows that non-opioid analgesics often provide adequate pain relief with fewer risks. The current study examined clinical decision support (CDS) as a tool for de-implementing opioid prescribing in dentistry.<h4>Methods</h4>This prospective, cluster-randomized trial examined CDS for dental pain management at 22 HealthPartners Dental Group clinics in Minnesota. Dental providers (n = 49) were randomized to deliver care using CDS, CDS with patient education materials (CDS-E), or standard practice (SP). Randomization was stratified by provider type (dentist vs. oral surgeon) and baseline opioid prescribing volume. Patient records of dental extractions were examined for January 2019 throug2023-01-01T00:00:00Z2023 Feb2026-05-28T20:09:45.265Z2025-04-07T13:01:05.991ZS-EPMC99130043676541410.1186/s13012-023-01262-7