{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18(2)"],"submitter":["Misawa N"],"pubmed_abstract":["<h4>Purpose</h4>To confirm the utility of ultra-widefield optical coherence tomography (W-OCT) for diagnosing uveitis.<h4>Method</h4>We retrospectively studied patients who had been diagnosed with uveitis and had undergone W-OCT. All patients had visited at Osaka Metropolitan University between January 2019 and January 2022. On W-OCT, vitreous opacity (\"W-OCT VO\") and the presence of vitreous cells (\"W-OCT Cells\") were identified by three specialists. We compared findings from ophthalmoscopy (\"Ophthalmoscopic findings\") and fluorescein angiography (\"FAG findings\") with those from W-OCT.<h4>Results</h4>This study investigated 132 eyes from 68 patients (34 males, 34 females; mean age, 53.97±22.71 years). Vitreous cells in posterior uveitis and panuveitis differed significantly between \"W-OCT Cells\" and \"Ophthalmoscopic findings\" for all cases (P = 0.00014). Vitreous opacities in posterior uveitis and panuveitis did not differ significantly between \"W-OCT VO\" and \"Ophthalmoscopic findings\" (P = 0.144) for all cases. Compared to \"Ophthalmoscopic findings\", \"W-OCT Cells\" offered 51.1% sensitivity and 66.7% specificity for all cases (p<0.01). Compared to \"Ophthalmoscopic findings\", \"W-OCT VO\" offered 78.6% sensitivity and 30% specificity for all cases (p = 0.19). In addition, \"W-OCT Cells\" did not differ significantly from \"FAG findings\" for all cases (P = 0.424).<h4>Conclusion</h4>W-OCT was shown to offer significantly greater sensitivity than ophthalmoscopy for detecting vitreous cells. The results of this study may add an option for the evaluation of uveitis."],"journal":["PloS one"],"pagination":["e0281714"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9916645"],"repository":["biostudies-literature"],"pubmed_title":["Relationship between ultra-widefield optical coherence tomography and ophthalmoscopy for detecting posterior inflammation in posterior uveitis and panuveitis."],"pmcid":["PMC9916645"],"pubmed_authors":["Honda S","Haruna Y","Misawa N","Sakai A","Tagami M"],"additional_accession":[]},"is_claimable":false,"name":"Relationship between ultra-widefield optical coherence tomography and ophthalmoscopy for detecting posterior inflammation in posterior uveitis and panuveitis.","description":"<h4>Purpose</h4>To confirm the utility of ultra-widefield optical coherence tomography (W-OCT) for diagnosing uveitis.<h4>Method</h4>We retrospectively studied patients who had been diagnosed with uveitis and had undergone W-OCT. All patients had visited at Osaka Metropolitan University between January 2019 and January 2022. On W-OCT, vitreous opacity (\"W-OCT VO\") and the presence of vitreous cells (\"W-OCT Cells\") were identified by three specialists. We compared findings from ophthalmoscopy (\"Ophthalmoscopic findings\") and fluorescein angiography (\"FAG findings\") with those from W-OCT.<h4>Results</h4>This study investigated 132 eyes from 68 patients (34 males, 34 females; mean age, 53.97±22.71 years). Vitreous cells in posterior uveitis and panuveitis differed significantly between \"W-OCT Cells\" and \"Ophthalmoscopic findings\" for all cases (P = 0.00014). Vitreous opacities in posterior uveitis and panuveitis did not differ significantly between \"W-OCT VO\" and \"Ophthalmoscopic findings\" (P = 0.144) for all cases. Compared to \"Ophthalmoscopic findings\", \"W-OCT Cells\" offered 51.1% sensitivity and 66.7% specificity for all cases (p<0.01). Compared to \"Ophthalmoscopic findings\", \"W-OCT VO\" offered 78.6% sensitivity and 30% specificity for all cases (p = 0.19). In addition, \"W-OCT Cells\" did not differ significantly from \"FAG findings\" for all cases (P = 0.424).<h4>Conclusion</h4>W-OCT was shown to offer significantly greater sensitivity than ophthalmoscopy for detecting vitreous cells. The results of this study may add an option for the evaluation of uveitis.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-18T15:53:18.461Z","creation":"2025-04-07T02:48:20.205Z"},"accession":"S-EPMC9916645","cross_references":{"pubmed":["36763630"],"doi":["10.1371/journal.pone.0281714"]}}