{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Victorson D"],"funding":["National Cancer Institute","NCI NIH HHS","National Institutes of Health"],"pagination":["107059"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9918709"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["125"],"pubmed_abstract":["<h4>Background</h4>Although active surveillance (AS) is an increasingly adopted treatment paradigm for management of very low risk prostate cancer, many men and their partners face a variety of AS-related psychosocial stressors. Stressors may include anxiety and fear of progression, which may negatively affect short- and long-term psychosocial adjustment and influence early withdrawal from AS in order to seek definitive therapies such as surgery or radiation. Here we describe the protocol for an NCI-funded trial, which seeks to examine the efficacy of mindfulness training compared with a time/attention-matched health promotion control condition in a geographically generalizable sample of men on AS and their spouses.<h4>Methods</h4>Using a randomized, controlled, partially double-blinded st"],"journal":["Contemporary clinical trials"],"pubmed_title":["Mindfulness-based stress reduction for men on active surveillance for prostate cancer and their spouses: Design and methodology of a randomized controlled trial."],"pmcid":["PMC9918709"],"funding_grant_id":["R01 CA193331","CA193193","T32 CA193193","NCT02871752","R01CA193331"],"pubmed_authors":["Horowitz B","Novakovic K","Brendler C","Murphy K","Morgan T","Victorson D","Addington E","Kutikov A","Jackson K","Sauer C","Kundu S"],"additional_accession":[]},"is_claimable":false,"name":"Mindfulness-based stress reduction for men on active surveillance for prostate cancer and their spouses: Design and methodology of a randomized controlled trial.","description":"<h4>Background</h4>Although active surveillance (AS) is an increasingly adopted treatment paradigm for management of very low risk prostate cancer, many men and their partners face a variety of AS-related psychosocial stressors. Stressors may include anxiety and fear of progression, which may negatively affect short- and long-term psychosocial adjustment and influence early withdrawal from AS in order to seek definitive therapies such as surgery or radiation. Here we describe the protocol for an NCI-funded trial, which seeks to examine the efficacy of mindfulness training compared with a time/attention-matched health promotion control condition in a geographically generalizable sample of men on AS and their spouses.<h4>Methods</h4>Using a randomized, controlled, partially double-blinded st","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-26T11:55:18.77Z","creation":"2025-02-19T04:59:45.068Z"},"accession":"S-EPMC9918709","cross_references":{"pubmed":["36563902"],"doi":["10.1016/j.cct.2022.107059"]}}