biostudies-literatureUnknown23(3)Magnaghi LRA novel 3 × 4 colorimetric sensing platform, named the chemometric-assisted litmus test (CLT), has been developed by covalently anchoring commercial pH indicators to ethylene vinyl alcohol (EVOH). The proposed device can be exploited for pH determinations in a wide range from 1 to 13 and in specific narrow ranges, achieving sufficient accuracy and errors below 0.5 pH units. The experimental procedure is simple, quick and reliable; equilibration is reached in less than 2 h, CLT pictures are acquired by a camera, and data treatment is performed applying chemometric techniques such as principal component analysis (PCA) and partial least square regression (PLS) to RGB indices.Sensors (Basel, Switzerland)1696https://www.ebi.ac.uk/biostudies/studies/S-EPMC9919261biostudies-literatureChemometric-Assisted Litmus Test: One Single Sensing Platform Adapted from 1-13 to Narrow pH Ranges.PMC9919261Guembe-Garcia MMagnaghi LRAlberti GQuadrelli PBiesuz RZanoni CfalseChemometric-Assisted Litmus Test: One Single Sensing Platform Adapted from 1-13 to Narrow pH Ranges.A novel 3 × 4 colorimetric sensing platform, named the chemometric-assisted litmus test (CLT), has been developed by covalently anchoring commercial pH indicators to ethylene vinyl alcohol (EVOH). The proposed device can be exploited for pH determinations in a wide range from 1 to 13 and in specific narrow ranges, achieving sufficient accuracy and errors below 0.5 pH units. The experimental procedure is simple, quick and reliable; equilibration is reached in less than 2 h, CLT pictures are acquired by a camera, and data treatment is performed applying chemometric techniques such as principal component analysis (PCA) and partial least square regression (PLS) to RGB indices.2023-01-01T00:00:00Z2023 Feb2025-05-29T22:23:30.713Z2025-05-29T22:23:30.713ZS-EPMC99192613677274010.3390/s23031696