{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cordeiro R"],"funding":["“Fundação para a Ciência e a Tecnologia” FCT/MCTES (PIDDAC)","Fundação para a Ciência e Tecnologia","Spanish Foundation for Science and Technology","the institutional scientific employment program-contract","Agencia de Inovacao"],"pagination":["781"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9919712"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(3)"],"pubmed_abstract":["Osteoarthritis is a highly prevalent disease worldwide that leads to cartilage loss. Tissue engineering, involving scaffolds, cells, and stimuli, has shown to be a promising strategy for its repair. Thus, this study aims to manufacture and characterise different scaffolds with poly(ε-caprolactone) (PCL) with commercial cellulose (microcrystalline (McC) and methyl cellulose (MC) or cellulose from agro-industrial residues (corncob (CcC)) and at different percentages, 1%, 2%, and 3%. PCL scaffolds were used as a control. Morphologically, the produced scaffolds presented porosities within the desired for cell incorporation (57% to 65%). When submitted to mechanical tests, the incorporation of cellulose affects the compression resistance of the majority of scaffolds. Regarding tensile strength,"],"journal":["Polymers"],"pubmed_title":["Cellulose-Based Scaffolds: A Comparative Study for Potential Application in Articular Cartilage."],"pmcid":["PMC9919712"],"funding_grant_id":["2022.09638.BD","CEECINST/00077/2021","UIDB/04044/2020; UIDP/04044/2020; 2022.09638.BD; Associate Laboratory ARISE LA/P/0112/2020; PAMI - ROTEIRO/0328/2013 (Nº 022158)","PAMI—ROTEIRO/0328/2013 (N° 022158)","BIODISCUS (CENTRE-01-0247-FEDER-039969)","UIDP/04044/2020","Associate Laboratory ARISE LA/P/0112/2020","UIDB/04044/2020"],"pubmed_authors":["Lopes B","Cordeiro R","Sousa P","Mauricio AC","Sousa AC","Alves N","Moura C","Alvites RD"],"additional_accession":[]},"is_claimable":false,"name":"Cellulose-Based Scaffolds: A Comparative Study for Potential Application in Articular Cartilage.","description":"Osteoarthritis is a highly prevalent disease worldwide that leads to cartilage loss. Tissue engineering, involving scaffolds, cells, and stimuli, has shown to be a promising strategy for its repair. Thus, this study aims to manufacture and characterise different scaffolds with poly(ε-caprolactone) (PCL) with commercial cellulose (microcrystalline (McC) and methyl cellulose (MC) or cellulose from agro-industrial residues (corncob (CcC)) and at different percentages, 1%, 2%, and 3%. PCL scaffolds were used as a control. Morphologically, the produced scaffolds presented porosities within the desired for cell incorporation (57% to 65%). When submitted to mechanical tests, the incorporation of cellulose affects the compression resistance of the majority of scaffolds. Regarding tensile strength,","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-08-17T03:07:36.159Z","creation":"2025-04-06T07:57:31.985Z"},"accession":"S-EPMC9919712","cross_references":{"pubmed":["36772083"],"doi":["10.3390/polym15030781"]}}