biostudies-literatureUnknown14Duijster JWMinisterie van Volksgezondheid, Welzijn en Sport<h4>Background</h4>Albeit the need for sex-disaggregated results of adverse events after immunization (AEFIs) is gaining attention since the COVID-19 pandemic, studies with emphasis on sexual dimorphism in response to COVID-19 vaccination are relatively scarce. This prospective cohort study aimed to assess differences in the incidence and course of reported AEFIs after COVID-19 vaccination between males and females in the Netherlands and provides a summary of sex-disaggregated outcomes in published literature.<h4>Methods</h4>Patient reported outcomes of AEFIs over a six month period following the first vaccination with BioNTech-Pfizer, AstraZeneca, Moderna or the Johnson&Johnson vaccine were collected in a Cohort Event Monitoring study. Logistic regression was used to assess differences inFrontiers in immunology1078736https://www.ebi.ac.uk/biostudies/studies/S-EPMC9922710biostudies-literatureSex-disaggregated outcomes of adverse events after COVID-19 vaccination: A Dutch cohort study and review of the literature.PMC9922710Raethke MPacelli SVan Hunsel FVan Balveren LRuijs LSKant ADuijster JWLieber TfalseSex-disaggregated outcomes of adverse events after COVID-19 vaccination: A Dutch cohort study and review of the literature.<h4>Background</h4>Albeit the need for sex-disaggregated results of adverse events after immunization (AEFIs) is gaining attention since the COVID-19 pandemic, studies with emphasis on sexual dimorphism in response to COVID-19 vaccination are relatively scarce. This prospective cohort study aimed to assess differences in the incidence and course of reported AEFIs after COVID-19 vaccination between males and females in the Netherlands and provides a summary of sex-disaggregated outcomes in published literature.<h4>Methods</h4>Patient reported outcomes of AEFIs over a six month period following the first vaccination with BioNTech-Pfizer, AstraZeneca, Moderna or the Johnson&Johnson vaccine were collected in a Cohort Event Monitoring study. Logistic regression was used to assess differences in2023-01-01T00:00:00Z20232026-03-17T15:56:25.202Z2025-04-04T11:16:40.554ZS-EPMC99227103679371510.3389/fimmu.2023.1078736