{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pillai MM"],"funding":["Indian Institute of Technology Bombay","Department of Biotechnology, Ministry of Science and Technology, India"],"pagination":["102025"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9922965"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10"],"pubmed_abstract":["Microneedle patches have been widely used in a minimally invasive manner for various drug delivery applications. However, for developing these microneedle patches, master molds are required, which are generally made of metal and are very expensive. Two-photon polymerization (2PP) technique can be used for fabricating microneedles more precisely and at a much lower cost. This study reports a novel strategy for developing microneedle master templates using the 2PP method. The main advantage of this technique is that there is no requirement for post-processing after laser writing, and that for the fabrication of polydimethylsiloxane (PDMS) molds, harsh chemical treatments such as silanization are not required. This is a one-step process for manufacturing of microneedle templates which allows "],"journal":["MethodsX"],"pubmed_title":["Two-photon polymerization based reusable master template to fabricate polymer microneedles for drug delivery."],"pmcid":["PMC9922965"],"funding_grant_id":["BT/INF/22/SP23026/2017"],"pubmed_authors":["Pillai MM","Tayalia P","Ajesh S"],"additional_accession":[]},"is_claimable":false,"name":"Two-photon polymerization based reusable master template to fabricate polymer microneedles for drug delivery.","description":"Microneedle patches have been widely used in a minimally invasive manner for various drug delivery applications. However, for developing these microneedle patches, master molds are required, which are generally made of metal and are very expensive. Two-photon polymerization (2PP) technique can be used for fabricating microneedles more precisely and at a much lower cost. This study reports a novel strategy for developing microneedle master templates using the 2PP method. The main advantage of this technique is that there is no requirement for post-processing after laser writing, and that for the fabrication of polydimethylsiloxane (PDMS) molds, harsh chemical treatments such as silanization are not required. This is a one-step process for manufacturing of microneedle templates which allows ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-20T01:35:01.724Z","creation":"2025-04-20T01:35:01.724Z"},"accession":"S-EPMC9922965","cross_references":{"pubmed":["36793674"],"doi":["10.1016/j.mex.2023.102025"]}}