biostudies-literatureUnknown13(2)Zhang L<h4>Objective</h4>Sepsis is a major contributor of intensive care units (ICUs) patient mortality. Prior investigations claimed that obesity enhances overall survival (OS) of septic patients. However, the reported results were inconsistent. This study examined the association between obesity and the 1-year mortality of septic patients.<h4>Design</h4>A retrospective cohort study.<h4>Setting</h4>The Medical Information Mart for Intensive Care III database.<h4>Participants</h4>3145 septic patients were separated into three distinct cohorts, based on their WHO body mass index (BMI) status.<h4>Outcomes</h4>Our primary endpoint was the 1-year mortality from the date of ICU hospitalization.<h4>Result</h4>1334 (42.4%) died within 1 year. The 1-year mortality rate was low in obese patients (38.8%), BMJ opene066526https://www.ebi.ac.uk/biostudies/studies/S-EPMC9923324biostudies-literatureAssociation between obesity and 1-year mortality in septic patients: a retrospective cohort study.PMC9923324Li CLihua HZhang LFang LfalseAssociation between obesity and 1-year mortality in septic patients: a retrospective cohort study.<h4>Objective</h4>Sepsis is a major contributor of intensive care units (ICUs) patient mortality. Prior investigations claimed that obesity enhances overall survival (OS) of septic patients. However, the reported results were inconsistent. This study examined the association between obesity and the 1-year mortality of septic patients.<h4>Design</h4>A retrospective cohort study.<h4>Setting</h4>The Medical Information Mart for Intensive Care III database.<h4>Participants</h4>3145 septic patients were separated into three distinct cohorts, based on their WHO body mass index (BMI) status.<h4>Outcomes</h4>Our primary endpoint was the 1-year mortality from the date of ICU hospitalization.<h4>Result</h4>1334 (42.4%) died within 1 year. The 1-year mortality rate was low in obese patients (38.8%), 2023-01-01T00:00:00Z2023 Feb2025-04-22T19:57:56.811Z2025-04-06T02:55:46.807ZS-EPMC99233243676472710.1136/bmjopen-2022-066526