{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["42(4)"],"submitter":["Ziyi Z"],"pubmed_abstract":["Objective
To investigate the short-term efficacy and safety outcomes following a sequential treatment with clearing heat and eliminating phlegm (CHEP) formula and tonifying Qi and activating blood circulation (TQABC) formula in patients with acute ischemic stroke (AIS) within a 72 h time window.Methods
In this randomized, multicenter, double-blinded, placebo-controlled trial, 500 participants will be randomly assigned in a ratio of 1∶1 to the CHEP+ TQABC group or control group. In addition to guideline-based standard medical care, participants in the treatment group will receive the CHEP formula for the first 5 consecutive days followed by the TQABC formula for another 10 consecutive days, while those in the control group will receive CHEP formula placebo and TQABC formula "],"journal":["Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan"],"pagination":["604-610"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9924680"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy and safety of a sequential treatment with clearing heat and eliminating phlegm and tonifying and activating blood circulation in treating acute ischemic stroke: study protocol for a randomized controlled trial."],"pmcid":["PMC9924680"],"pubmed_authors":["Lejun LI","Xiangzhe L","Yefeng C","Mingzhe HU","Ying G","Chunhua W","Ziyi Z","Jie C","Yuanqi Z","Huili Z","Xiaofei YU","Hongwei AN","Qing S","Can W","Xinchun Z","Wenguo H","Huijuan W","Junbin C"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy and safety of a sequential treatment with clearing heat and eliminating phlegm and tonifying and activating blood circulation in treating acute ischemic stroke: study protocol for a randomized controlled trial.","description":"Objective
To investigate the short-term efficacy and safety outcomes following a sequential treatment with clearing heat and eliminating phlegm (CHEP) formula and tonifying Qi and activating blood circulation (TQABC) formula in patients with acute ischemic stroke (AIS) within a 72 h time window.Methods
In this randomized, multicenter, double-blinded, placebo-controlled trial, 500 participants will be randomly assigned in a ratio of 1∶1 to the CHEP+ TQABC group or control group. In addition to guideline-based standard medical care, participants in the treatment group will receive the CHEP formula for the first 5 consecutive days followed by the TQABC formula for another 10 consecutive days, while those in the control group will receive CHEP formula placebo and TQABC formula ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T14:24:21.041Z","creation":"2024-11-12T18:11:28.826Z"},"accession":"S-EPMC9924680","cross_references":{"pubmed":["35848977"],"doi":["10.19852/j.cnki.jtcm.20220617.003"]}}