biostudies-literatureUnknown31(6)Van Steijvoort EResearch Fund FlandersReproductive genetic carrier screening (RGCS) allows for the identification of couples who have an increased likelihood of conceiving a child with a particular autosomal recessive or X-linked condition. The aim of this study was to assess the level of satisfaction, anxiety, knowledge retention, psychosocial and counseling-related aspects among couples who chose to have RGCS. Participants were initially informed about their screening results by telephone. After obtaining a written report of test results, participants were asked to complete an individual self-administered questionnaire. All participants (n = 67) felt they had enough information to make an informed choice. None of the participants regretted their choice to have RGCS. Test results were most often shared with parents (61%) or siblings (37%). Our findings demonstrate that the information/counseling and reporting strategy that was used in the context of this study led to high participant satisfaction, an increase in knowledge over time and favorable psychosocial and counseling-related outcomes.European journal of human genetics : EJHG696-702https://www.ebi.ac.uk/biostudies/studies/S-EPMC9928592biostudies-literatureExperiences of nonpregnant couples after receiving reproductive genetic carrier screening results in Belgium.PMC9928592Vandecruys HMatthijs GVan Steijvoort EPeeraer KBorry PVerguts JPeeters HfalseExperiences of nonpregnant couples after receiving reproductive genetic carrier screening results in Belgium.Reproductive genetic carrier screening (RGCS) allows for the identification of couples who have an increased likelihood of conceiving a child with a particular autosomal recessive or X-linked condition. The aim of this study was to assess the level of satisfaction, anxiety, knowledge retention, psychosocial and counseling-related aspects among couples who chose to have RGCS. Participants were initially informed about their screening results by telephone. After obtaining a written report of test results, participants were asked to complete an individual self-administered questionnaire. All participants (n = 67) felt they had enough information to make an informed choice. None of the participants regretted their choice to have RGCS. Test results were most often shared with parents (61%) or siblings (37%). Our findings demonstrate that the information/counseling and reporting strategy that was used in the context of this study led to high participant satisfaction, an increase in knowledge over time and favorable psychosocial and counseling-related outcomes.2023-01-01T00:00:00Z2023 Jun2025-04-04T08:58:14.727Z2025-04-04T08:58:14.727ZS-EPMC99285923678814410.1038/s41431-023-01310-2