{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29"],"submitter":["Chen T"],"pubmed_abstract":["<b>Aims:</b> We present a 5-case series of low-grade oncocytic tumour of the kidney to further discuss their clinicopathological characteristics. <b>Methods and results:</b> Five patients were included in this study. There were three females and two males aged 45-66 years, with a median age of 65 years. Four tumours were located in the right kidney, and one was located in the left kidney. Most of the tumour sections were yellow-brown in colour. Tumour sizes ranged from 2.5 to 4.5 cm, with a median size of 3 cm. Microscopically, the tumours were well-circumscribed but lacked a fibrous capsule; the tumours consisted of monomorphous oncocytic cells arranged mainly in solid and nested architectural patterns. The tumour cells had uniformly round to oval nuclei and often had perinuclear halos bu"],"journal":["Pathology oncology research : POR"],"pagination":["1610852"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9928737"],"repository":["biostudies-literature"],"pubmed_title":["Low-grade oncocytic tumour (LOT) of the kidney is characterised by GATA3 positivity, FOXI1 negativity and mTOR pathway mutations."],"pmcid":["PMC9928737"],"pubmed_authors":["Peng Y","Wu C","Lei T","Wang H","Chen T","Shi Y"],"additional_accession":[]},"is_claimable":false,"name":"Low-grade oncocytic tumour (LOT) of the kidney is characterised by GATA3 positivity, FOXI1 negativity and mTOR pathway mutations.","description":"<b>Aims:</b> We present a 5-case series of low-grade oncocytic tumour of the kidney to further discuss their clinicopathological characteristics. <b>Methods and results:</b> Five patients were included in this study. There were three females and two males aged 45-66 years, with a median age of 65 years. Four tumours were located in the right kidney, and one was located in the left kidney. Most of the tumour sections were yellow-brown in colour. Tumour sizes ranged from 2.5 to 4.5 cm, with a median size of 3 cm. Microscopically, the tumours were well-circumscribed but lacked a fibrous capsule; the tumours consisted of monomorphous oncocytic cells arranged mainly in solid and nested architectural patterns. The tumour cells had uniformly round to oval nuclei and often had perinuclear halos bu","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2026-04-08T14:35:52.273Z","creation":"2025-02-18T23:44:17.881Z"},"accession":"S-EPMC9928737","cross_references":{"pubmed":["36816543"],"doi":["10.3389/pore.2023.1610852"]}}