biostudies-literatureMoreira JPCFundação para a Ciência e a Tecnologia24https://www.ebi.ac.uk/biostudies/studies/S-EPMC9930230biostudies-literatureUnknown16(1)<h4>Background</h4>Developing new bioprocesses to produce chemicals and fuels with reduced production costs will greatly facilitate the replacement of fossil-based raw materials. In most fermentation bioprocesses, the feedstock usually represents the highest cost, which becomes the target for cost reduction. Additionally, the biorefinery concept advocates revenue growth from the production of several compounds using the same feedstock. Taken together, the production of bio commodities from low-cost gas streams containing CO, CO₂, and H₂, obtained from the gasification of any carbon-containing waste streams or off-gases from heavy industry (steel mills, processing plants, or refineries), embodies an opportunity for affordable and renewable chemical production. To achieBiotechnology for biofuels and bioproductsDeveloping a genetic engineering method for Acetobacterium wieringae to expand one-carbon valorization pathways.PMC9930230UIDB/04469/2020Domingues LHeap JTAlves JIMoreira JPCfalseDeveloping a genetic engineering method for Acetobacterium wieringae to expand one-carbon valorization pathways.<h4>Background</h4>Developing new bioprocesses to produce chemicals and fuels with reduced production costs will greatly facilitate the replacement of fossil-based raw materials. In most fermentation bioprocesses, the feedstock usually represents the highest cost, which becomes the target for cost reduction. Additionally, the biorefinery concept advocates revenue growth from the production of several compounds using the same feedstock. Taken together, the production of bio commodities from low-cost gas streams containing CO, CO₂, and H₂, obtained from the gasification of any carbon-containing waste streams or off-gases from heavy industry (steel mills, processing plants, or refineries), embodies an opportunity for affordable and renewable chemical production. To achie2023-01-01T00:00:00Z2023 Feb2025-04-18T13:38:21.384Z2025-04-06T23:25:19.37ZS-EPMC99302303678858710.1186/s13068-023-02259-6