{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cansler HL"],"funding":["NIDA NIH HHS","NIDCD NIH HHS","NINDS NIH HHS","National Institutes of Health"],"pagination":["1504-1526"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9930634"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(4)"],"pubmed_abstract":["<h4>Background</h4>Sensory perception is profoundly shaped by attention. Attending to an odor strongly regulates if and how it is perceived - yet the brain systems involved in this process are unknown. Here we report integration of the medial prefrontal cortex (mPFC), a collection of brain regions integral to attention, with the olfactory system in the context of selective attention to odors.<h4>Methods</h4>First, we used tracing methods to establish the tubular striatum (TuS, also known as the olfactory tubercle) as the primary olfactory region to receive direct mPFC input in rats. Next, we recorded (i) local field potentials from the olfactory bulb (OB), mPFC, and TuS, or (ii) sniffing, while rats completed an olfactory selective attention task.<h4>Results</h4>Gamma power and coupling of"],"journal":["Cerebral cortex (New York, N.Y. : 1991)"],"pubmed_title":["Organization and engagement of a prefrontal-olfactory network during olfactory selective attention."],"pmcid":["PMC9930634"],"funding_grant_id":["R01 DA049545","R01 DA049449","R01NS117061","R01DC006213","R01 NS117061","F32DC018232","R01DA049449","R01DA049545","R01 DC006213","R01DC014443","F32 DC018232","R01 DC016519","R01DC016519"],"pubmed_authors":["Ma M","Carlson KS","Khan WT","Wesson DW","Cansler HL","In 't Zandt EE"],"additional_accession":[]},"is_claimable":false,"name":"Organization and engagement of a prefrontal-olfactory network during olfactory selective attention.","description":"<h4>Background</h4>Sensory perception is profoundly shaped by attention. Attending to an odor strongly regulates if and how it is perceived - yet the brain systems involved in this process are unknown. Here we report integration of the medial prefrontal cortex (mPFC), a collection of brain regions integral to attention, with the olfactory system in the context of selective attention to odors.<h4>Methods</h4>First, we used tracing methods to establish the tubular striatum (TuS, also known as the olfactory tubercle) as the primary olfactory region to receive direct mPFC input in rats. Next, we recorded (i) local field potentials from the olfactory bulb (OB), mPFC, and TuS, or (ii) sniffing, while rats completed an olfactory selective attention task.<h4>Results</h4>Gamma power and coupling of","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-03-15T13:24:37.763Z","creation":"2025-04-06T02:29:47.326Z"},"accession":"S-EPMC9930634","cross_references":{"pubmed":["35511680"],"doi":["10.1093/cercor/bhac153"]}}