{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["43(4)"],"submitter":["Gragnani L"],"pubmed_abstract":["<h4>Purpose</h4>Mixed cryoglobulinemia syndrome (MCs) is a rare immunoproliferative systemic disorder with cutaneous and multiple organ involvement. Our multicenter survey study aimed to investigate the prevalence and outcome of COVID-19 and the safety and immunogenicity of COVID-19 vaccines in a large MCs series.<h4>Methods</h4>The survey included 430 unselected MCs patients (130 M, 300 F; mean age 70 ± 10.96 years) consecutively collected at 11 Italian referral centers. Disease classification, clinico-serological assessment, COVID-19 tests, and vaccination immunogenicity were carried out according to current methodologies.<h4>Results</h4>A significantly higher prevalence of COVID-19 was found in MCs patients compared to Italian general population (11.9% vs 8.0%, p < 0.005), and the use o"],"journal":["Journal of clinical immunology"],"pagination":["680-691"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9933006"],"repository":["biostudies-literature"],"pubmed_title":["COVID-19 and Mixed Cryoglobulinemia Syndrome: Long-Term Survey Study on the Prevalence and Outcome, Vaccine Safety, and Immunogenicity."],"pmcid":["PMC9933006"],"pubmed_authors":["Gragnani L","Ruscitti P","Casato M","Urraro T","Santini SA","Cacciapaglia F","Ferri C","Scarpato S","Treppo E","Iannone F","Mazzaro C","Lauletta G","Petraccia L","Antonelli A","Puccetti L","Del Frate G","Scorpiniti D","Monti M","Visentini M","Basili S","Cusano G","Naclerio C","Elia G","Tavoni A","Marri S","Fallahi P","Raimondo V","Quartuccio L","Zignego AL","Di Cola I","Lorini S"],"additional_accession":[]},"is_claimable":false,"name":"COVID-19 and Mixed Cryoglobulinemia Syndrome: Long-Term Survey Study on the Prevalence and Outcome, Vaccine Safety, and Immunogenicity.","description":"<h4>Purpose</h4>Mixed cryoglobulinemia syndrome (MCs) is a rare immunoproliferative systemic disorder with cutaneous and multiple organ involvement. Our multicenter survey study aimed to investigate the prevalence and outcome of COVID-19 and the safety and immunogenicity of COVID-19 vaccines in a large MCs series.<h4>Methods</h4>The survey included 430 unselected MCs patients (130 M, 300 F; mean age 70 ± 10.96 years) consecutively collected at 11 Italian referral centers. Disease classification, clinico-serological assessment, COVID-19 tests, and vaccination immunogenicity were carried out according to current methodologies.<h4>Results</h4>A significantly higher prevalence of COVID-19 was found in MCs patients compared to Italian general population (11.9% vs 8.0%, p < 0.005), and the use o","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-22T20:57:47.887Z","creation":"2024-11-06T12:50:35.218Z"},"accession":"S-EPMC9933006","cross_references":{"pubmed":["36795264"],"doi":["10.1007/s10875-023-01444-4"]}}