{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["De B"],"funding":["NCATS NIH HHS","AHRQ HHS","NCI NIH HHS"],"pagination":["1226-1239"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9933910"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["208(6)"],"pubmed_abstract":["<h4>Purpose</h4>Data comparing radical prostatectomy and external beam radiation therapy with low dose rate brachytherapy boost are lacking. To better guide shared decision making regarding treatment, we compared patient reported outcomes through 5 years following radical prostatectomy or external beam radiation therapy with low dose rate brachytherapy boost for localized prostate cancer.<h4>Materials and methods</h4>From 2011-2012, men aged <80 years with localized prostate adenocarcinoma were enrolled and followed longitudinally. Patient reported outcomes included the Expanded Prostate Index Composite. Regression models adjusted for baseline scores and covariates were constructed.<h4>Results</h4>The study population included 112 men treated with external beam radiation therapy with low d"],"journal":["The Journal of urology"],"pubmed_title":["Patient-reported Outcomes After External Beam Radiotherapy With Low Dose Rate Brachytherapy Boost vs Radical Prostatectomy for Localized Prostate Cancer: Five-year Results From a Prospective Comparative Effectiveness Study."],"pmcid":["PMC9933910"],"funding_grant_id":["R01 HS019356","P30 CA016672","HHSN261201800016C","R01 HS022640","HHSN261201800016I","UL1 TR000445","R01 CA230352"],"pubmed_authors":["Hashibe M","Pasalic D","De B","Koyama T","Wallis CJD","Paddock LE","Cooperberg MR","Tang C","Goodman M","O'Neil BB","Greenfield S","Zhao Z","Hamilton AS","Wu XC","Stroup A","Barocas DA","Hoffman KE","Huang LC","Kaplan SH","Penson DF"],"additional_accession":[]},"is_claimable":false,"name":"Patient-reported Outcomes After External Beam Radiotherapy With Low Dose Rate Brachytherapy Boost vs Radical Prostatectomy for Localized Prostate Cancer: Five-year Results From a Prospective Comparative Effectiveness Study.","description":"<h4>Purpose</h4>Data comparing radical prostatectomy and external beam radiation therapy with low dose rate brachytherapy boost are lacking. To better guide shared decision making regarding treatment, we compared patient reported outcomes through 5 years following radical prostatectomy or external beam radiation therapy with low dose rate brachytherapy boost for localized prostate cancer.<h4>Materials and methods</h4>From 2011-2012, men aged <80 years with localized prostate adenocarcinoma were enrolled and followed longitudinally. Patient reported outcomes included the Expanded Prostate Index Composite. Regression models adjusted for baseline scores and covariates were constructed.<h4>Results</h4>The study population included 112 men treated with external beam radiation therapy with low d","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2026-05-29T07:37:52.37Z","creation":"2025-02-19T01:16:57.044Z"},"accession":"S-EPMC9933910","cross_references":{"pubmed":["36006050"],"doi":["10.1097/ju.0000000000002902","10.1097/JU.0000000000002902"]}}