biostudies-literatureUnknown2023Hong ZWound healing due to skin defects is a growing clinical concern. Especially when infection occurs, it not only leads to impair healing of the wound but even leads to the occurrence of death. In this study, a self-healing supramolecular hydrogel with antibacterial abilities was developed for wound healing. The supramolecular hydrogels inherited excellent self-healing and mechanical properties are produced by the polymerization of N-acryloyl glycinamide monomers which carries a lot of amides. In addition, excellent antibacterial properties are obtained by integrating silver nanoparticles (Ag NPs) into the hydrogels. The resultant hydrogel has a demonstrated ability in superior mechanical properties, including stretchability and self-healing. Also, the good biocompatibility and antibacterial Journal of healthcare engineering7109766https://www.ebi.ac.uk/biostudies/studies/S-EPMC9935882biostudies-literatureSelf-Healing Supramolecular Hydrogels with Antibacterial Abilities for Wound Healing.PMC9935882Ren HWu LZhang ZZhang JHong ZRen JGu GWang GWu XfalseSelf-Healing Supramolecular Hydrogels with Antibacterial Abilities for Wound Healing.Wound healing due to skin defects is a growing clinical concern. Especially when infection occurs, it not only leads to impair healing of the wound but even leads to the occurrence of death. In this study, a self-healing supramolecular hydrogel with antibacterial abilities was developed for wound healing. The supramolecular hydrogels inherited excellent self-healing and mechanical properties are produced by the polymerization of N-acryloyl glycinamide monomers which carries a lot of amides. In addition, excellent antibacterial properties are obtained by integrating silver nanoparticles (Ag NPs) into the hydrogels. The resultant hydrogel has a demonstrated ability in superior mechanical properties, including stretchability and self-healing. Also, the good biocompatibility and antibacterial 2023-01-01T00:00:00Z20232025-04-26T15:02:14.109Z2025-04-06T14:45:59.305ZS-EPMC99358823681838110.1155/2023/7109766